2-Fluoronitrobenzene

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2-Fluoronitrobenzene
2-Fluornitrobenzol.svg
Names
Other names
1-fluoro-2-nitrobenzene, 2-nitrofluorobenzene
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
ECHA InfoCard 100.014.626 OOjs UI icon edit-ltr-progressive.svg
EC Number
  • 216-088-0
PubChem CID
UNII
  • InChI=1S/C6H4FNO2/c7-5-3-1-2-4-6(5)8(9)10/h1-4H
    Key: PWKNBLFSJAVFAB-UHFFFAOYSA-N
  • C1=CC=C(C(=C1)[N+](=O)[O-])F
Properties
C6H4FNO2
Molar mass 141.101 g·mol−1
Appearancecolorless liquid
Density 1.3291 g/cm3
Melting point −6 °C (21 °F; 267 K)
Boiling point 215 °C (419 °F; 488 K)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

2-Fluoronitrobenzene is an organic compound with the formula FC6H4NO2. It is one of three isomeric fluoronitrobenzenes. [1] A colorless liquid, it is prepared from 2-nitrochlorobenzene using the Halex process:

O2NC6H4Cl + KF → O2NC6H4F + KCl

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4-Nitrochlorobenzene is the organic compound with the formula ClC6H4NO2. It is a pale yellow solid. 4-Nitrochlorobenzene is a common intermediate in the production of a number of industrially useful compounds, including antioxidants commonly found in rubber. Other isomers with the formula ClC6H4NO2 include 2-nitrochlorobenzene and 3-nitrochlorobenzene.

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2-Nitrochlorobenzene is an organic compound with the formula ClC6H4NO2. It is one of three isomeric nitrochlorobenzenes. It is a yellow crystalline solid that is important as a precursor to other compounds due to its two functional groups.

In chemistry, the Halex process is used to convert aromatic chlorides to the corresponding aromatic fluorides. The process entails Halide exchange, hence the name. The reaction conditions call for hot solution of the aryl chloride and anhydrous potassium fluoride. Typical solvents are dimethylsulfoxide, dimethylformamide, and sulfolane. Potassium chloride is generated in the process. The reaction is mainly applied to nitro-substituted aryl chlorides.

Fluoronitrobenzene may refer to three compounds with the formula FC6H4NO2:

4-Fluoronitrobenzene is an organic compound with the formula FC6H4NO2. It is one of three isomeric fluoronitrobenzenes. A yellow oil, it is prepared from 4-nitrochlorobenzene using the Halex process:

References

  1. Gerald Booth, "Nitro Compounds, Aromatic" in Ullmann's Encyclopedia of Industrial Chemistry, Wiley-VCH: Weinheim, 2005. doi : 10.1002/14356007.a17_411