The 2000 season was the Kansas City Chiefs' 31st in the National Football League (NFL), their 41st overall and their second and final season under head coach Gunther Cunningham. They failed to improve on their 9–7 record from 1999 and finished the season 7–9, marked by a series of on and off-field struggles and incidents.
The 2004 season was the Houston Texans' third in the National Football League, all of which they had spent under head coach Dom Capers. The team finished 7–9, two games better than the previous season, and came third in the AFC South, the first time they had not finished bottom. The Texans also earned their first victory over the Tennessee Titans, the franchise previously known as the Oilers, who had left Houston after the 1996 season.
The 2005 Houston Texans season was the franchise's 4th season in the National Football League and the 4th and final season under head coach Dom Capers. The Texans completed the season with the worst record in franchise history. This led to the Texans obtaining the first selection in the NFL draft for the second time since the franchise formed in 2002. The team fired head coach Dom Capers after the season; he was replaced by Denver Broncos offensive coordinator Gary Kubiak, who would coach the team up until 2013. Their Week 3 game was postponed due to Hurricane Rita. The Texans failed to win a division game, and went 0–8 on the road for the first time in franchise history.
The 2008 Tennessee Titans season was the team's 49th season and 39th in the National Football League (NFL), their 12th in Tennessee, and their tenth as the Titans.
The 2009 Tennessee Titans season was the 50th season for the original American Football League (AFL) team, their 40th in the National Football League (NFL), and 13th in Tennessee. The Titans aimed to equal or improve on their 2008 NFL-best 13–3 record; however, they lost the first six games of the season. The Titans switched to Vince Young as starting quarterback and won eight out of their remaining ten games, losing only to the Indianapolis Colts and San Diego Chargers. The 42–17 loss to the Chargers in Week 16 eliminated the team from playoff contention for the first time since 2006.
The 2010 Tennessee Titans season was the team's 41st season in the National Football League (NFL), their 51st overall and their 14th season in Tennessee. The Titans hoped to improve on their 8–8 record from the 2009 season, but they failed to do so and ended up finishing 6-10. They started the season 5-2, but lost the next 8 of 9. This was the Titans’ final season under head coach Jeff Fisher, who resigned on January 27, 2011 after 17 seasons with the team.
The 2011 season was the Houston Texans' 10th in the National Football League (NFL) and their sixth under head coach Gary Kubiak. The Texans improved on their record from the 2010 season, despite losing starting quarterback Matt Schaub & backup Matt Leinart to season ending injuries. Third stringer T.J. Yates filled in, and earned the franchise's first playoff berth by defeating the Cincinnati Bengals 20–19 in Week 14 and clinching the AFC South. It also assured the Texans of at least one playoff game at home—the first NFL playoff game in Houston since 1993. After reaching the Divisional match against the Baltimore Ravens, the Texans suffered their maiden loss in the NFL Playoffs, losing 20–13.
The 2011 season was the Tennessee Titans' 42nd in the National Football League (NFL), their 52nd overall and their 15th in the state of Tennessee. It was also their first season under head coach Mike Munchak, replacing longtime head coach Jeff Fisher, who resigned on January 27 after 17 seasons. The team improved on their 6–10 record from 2010 and finished tied with the Cincinnati Bengals for the last playoff spot, but lost the tiebreaker due to their 24–17 loss to the Bengals in Week 9, missing the playoffs for a third consecutive season.
The 2012 season was the Jacksonville Jaguars' 18th in the National Football League (NFL), their first under the ownership of Shahid Khan, and the only season for head coach Mike Mularkey. The Jaguars entered the season hoping to improve on their 5–11 record from 2011 and return to the playoffs for the first time since 2007, but did not and were eliminated from postseason contention. This season marked the third time in the last five seasons in which the Jaguars finished fourth in the AFC South. The Jaguars finished with a 2–14 record, not only tying the Kansas City Chiefs for the league's worst record of 2012, but it would also be the worst in franchise history until the team went 1–15 in 2020. Their 1–7 record at home was also their worst home record in team history.
The 2013 season was the Houston Texans' 12th in the National Football League (NFL). They failed to improve upon their 12–4 record from 2012, suffering through a season-ending 14-game losing streak following a 2–0 start and missing the playoffs for the first time since 2010. Head coach Gary Kubiak was fired after eight seasons following their eleventh loss. Defensive coordinator Wade Phillips was named the interim head coach for the final three games of the season. Out of the 14 games lost by the Texans this year, nine of them were by one score, marking a record amount of one-score losses for the franchise. Their 14-game losing streak is the worst in team history. Coming off a franchise-best 12–4 record just the year before, the Texans tie a league record with Houston's previous team, the Oilers for the biggest season-to-season decline in win total. On January 3, 2014, claiming, "I'm ready to kick 2013 the hell out the door", Texans owner Robert McNair announced that former Penn State head coach Bill O'Brien would be the Texans' third head coach.
The 2013 season was the Tennessee Titans' 44th in the National Football League (NFL), their 54th overall, their 17th in the state of Tennessee, and their third and final season under head coach Mike Munchak. It was also their final season under the ownership of founder Bud Adams, who died on October 21. The Titans slightly improved on their 6–10 record from 2012 but missed the playoffs for a fifth consecutive season.
The 2014 season was the Tennessee Titans' 45th in the National Football League (NFL), their 55th overall and their 18th in the state of Tennessee. It was also their first season under head coach Ken Whisenhunt, as well as the first full season since the death of longtime owner Bud Adams, who died during the 2013 season. The Titans finished the season with 10 consecutive losses to finish with a 2–14 record, not only tying the Tampa Bay Buccaneers for the league's worst record, but also the Titans' worst season since 1994, when the franchise was known as the Houston Oilers.
The 2015 season was the Tennessee Titans' 46th in the National Football League (NFL), their 56th overall and their 19th in the state of Tennessee. Second-year head coach Ken Whisenhunt was fired on November 3 following a 1–6 start, and was replaced by tight ends coach Mike Mularkey on an interim basis. Despite slightly improving from their 2–14 season from the previous year, finishing with a 3–13 record, they finished with a lower Strength of Schedule, thus earning the right to the top pick in the 2016 NFL draft, later trading it to the Los Angeles Rams.
The 2016 season was the Tennessee Titans' 47th in the National Football League (NFL) and their 57th overall. It also marked the franchise's 20th season in the state of Tennessee as well as the first full season under head coach Mike Mularkey, who served as the team's interim head coach for the last nine games of the 2015 season.
The 2017 season was the Tennessee Titans' 48th in the National Football League (NFL) and the 58th overall. It also marked the franchise's 21st season in the state of Tennessee as well as the second full season under head coach Mike Mularkey. They equaled their record from a year ago, and not only that, with a 15–10 win over the Jacksonville Jaguars in Week 17, they clinched their first playoff berth since 2008. In the first round, the Titans rallied from a 21–3 halftime deficit against the Chiefs to win 22–21, winning their first playoff game since 2003. However, they were defeated by the New England Patriots in the divisional round by the score of 35–14. Despite making the playoffs and winning a playoff game, this would be Mularkey's final year coaching the Titans, as they parted ways after the season ended. This is also the last season where the Titans wore their uniform design since 1999.
The 2018 season was the Tennessee Titans' 49th in the National Football League (NFL) and their 59th overall. It also marked the franchise's 22nd season in the state of Tennessee, their first under head coach Mike Vrabel, and the first with new uniforms and blue helmets, as they have worn white helmets since the club was based in Houston, Texas. This season marked the third of four straight in which the Titans finished 9–7. The Titans failed to qualify for the postseason after losing a Week 17 win-and-in contest against their division rival Indianapolis Colts.
The 2020 season was the Tennessee Titans' 51st in the National Football League (NFL), their 61st overall, their 24th in the state of Tennessee, and their third under head coach Mike Vrabel. After starting the season 5–0, their first since the 2008 season, the Titans improved upon their 9–7 season from the previous 4 years and earned their first double-digit winning season and division title since 2008. The Titans finished tied with the Indianapolis Colts for the AFC South division title, but won the tiebreaker based on record vs. division opponents. In the Wild Card Round, the Titans blew a 10–0 lead and were upset by Lamar Jackson's Baltimore Ravens, 20–13. As of 2024, they are the most recent AFC division champion to lose in the Wild Card round.
The 2021 season was the Tennessee Titans' 52nd season in the National Football League (NFL), their 62nd overall, their 25th in the state of Tennessee, and their fourth under head coach Mike Vrabel. After a 34–3 win over the Miami Dolphins in Week 17, the Titans clinched the AFC South for the second consecutive season. It would be the first time since 1960–1962 that the franchise would win its division in back-to-back seasons. The Titans finished 12–5, improving on their 11–5 record from the prior year and earning the AFC's No. 1 seed in the playoffs for the first time since 2008. The season ended with a 19–16 loss to eventual AFC champion Cincinnati Bengals, the third consecutive playoff loss.
The 2022 season was the Tennessee Titans' 53rd in the National Football League (NFL), their 63rd overall, their 26th in the state of Tennessee and their fifth under head coach Mike Vrabel.
The 2023 season was the Tennessee Titans' 54th season in the National Football League (NFL), their 64th overall, their 27th in the state of Tennessee and their sixth and final under head coach Mike Vrabel. The Titans attempted to improve upon their underachieving 7–10 record from last year. They also attempted to make it back to the playoffs after missing them for the first time since 2018. However, after a Week 15 loss to the Houston Texans in overtime, they were eliminated from playoff contention for the second year in a row. The following week they were locked to last in the AFC South after losing to the Seattle Seahawks 20–17 in Week 16, and they failed to improve on their 7–10 record from 2022. The Titans would lose many close games this year, with 7 out of their 11 losses being decided 8 points or less. They also lost 5 of their games by a combined 14 points. On January 9, the Titans fired Vrabel.