| 2018 Open Harmonie mutuelle | |
|---|---|
| Date | 26 March – 1 April |
| Edition | 15th |
| Draw | 32S / 16D |
| Surface | Hard |
| Location | Saint-Brieuc, France |
| Champions | |
| Singles | |
 Ričardas Berankis | |
| Doubles | |
 Sander Arends /  Tristan-Samuel Weissborn | |
The 2018 Open Harmonie mutuelle was a professional tennis tournament played on hard courts. It was the fifteenth edition of the tournament which was part of the 2018 ATP Challenger Tour. It took place in Saint-Brieuc, France between 26 March and 1 April 2018.
| Country | Player | Rank1 | Seed |
|---|---|---|---|
 CYP | Marcos Baghdatis | 82 | 1 |
| LTU | Ričardas Berankis | 103 | 2 |
 SVK | Lukáš Lacko | 104 | 3 |
 UKR | Sergiy Stakhovsky | 118 | 4 |
 GER | Oscar Otte | 129 | 5 |
 SWE | Elias Ymer | 133 | 6 |
 FRA | Corentin Moutet | 138 | 7 |
 EST | Jürgen Zopp | 147 | 8 |
The following players received wildcards into the singles main draw:
The following players received entry into the singles main draw as special exempts:
The following players received entry from the qualifying draw:
Ričardas Berankis def. Constant Lestienne 6–2, 5–7, 6–4. Sander Arends / Tristan-Samuel Weissborn def. 
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