| 2018 Santaizi ATP Challenger | |
|---|---|
| Date | 9–15 April |
| Edition | 5th |
| Draw | 32S / 16D |
| Surface | Carpet (indoors) |
| Location | Taipei, Taiwan |
| Champions | |
| Singles | |
 Yuki Bhambri | |
| Doubles | |
 Matthew Ebden / Andrew Whittington | |
The 2018 Santaizi ATP Challenger was a professional tennis tournament played on indoor carpet courts. It was the fifth edition of the tournament which was part of the 2018 ATP Challenger Tour. It took place in Taipei, Taiwan between 9 and 15 April.
| Country | Player | Rank1 | Seed |
|---|---|---|---|
| AUS | Matthew Ebden | 77 | 1 |
 RUS | Evgeny Donskoy | 85 | 2 |
 ISR | Dudi Sela | 98 | 3 |
| IND | Yuki Bhambri | 105 | 4 |
 FRA | Quentin Halys | 115 | 5 |
| IND | Ramkumar Ramanathan | 132 | 6 |
 JPN | Go Soeda | 153 | 7 |
| JPN | Tatsuma Ito | 155 | 8 |
The following players received wildcards into the singles main draw:
The following players received entry into the singles main draw using protected rankings:
The following players received entry from the qualifying draw:
Thomas Fancutt 
Lo Chien-hsun
Ruan Roelofse Shuichi SekiguchiThe following players received entry as lucky losers:
Jacob Grills Sasikumar Mukund Yuki Bhambri def. Ramkumar Ramanathan 6–3, 6–4. Matthew Ebden / Andrew Whittington def. Prajnesh Gunneswaran / Saketh Myneni 6–4, 5–7, [10–6].