| 2019 Columbus Challenger II | |
|---|---|
| Date | 10–16 June |
| Edition | 7th |
| Draw | 48S / 16D |
| Surface | Hard |
| Location | Columbus, United States |
| Champions | |
| Singles | |
 Mikael Torpegaard | |
| Doubles | |
 Roberto Maytín /  Jackson Withrow | |
The 2019 Columbus Challenger II was a professional tennis tournament played on hard courts. It was the seventh edition of the tournament which was part of the 2019 ATP Challenger Tour. It took place in Columbus, United States between 10 and 16 June 2019.
| Country | Player | Rank1 | Seed |
|---|---|---|---|
| USA | Michael Mmoh | 141 | 1 |
 JPN | Yasutaka Uchiyama | 179 | 2 |
 ECU | Emilio Gómez | 191 | 3 |
| USA | Donald Young | 193 | 4 |
 BAR | |||
 ISR | Dudi Sela | 209 | 6 |
| ECU | Roberto Quiroz | 217 | 7 |
| DEN | Mikael Torpegaard | 218 | 8 |
| USA | Tim Smyczek | 224 | 9 |
 CHN | Li Zhe | 239 | 10 |
 KOR | Lee Duck-hee | 243 | 11 |
| USA | Thai-Son Kwiatkowski | 248 | 12 |
 CAN | Filip Peliwo | 267 | 13 |
| USA | J. J. Wolf | 270 | 14 |
| USA | Collin Altamirano | 277 | 15 |
 BRA | João Menezes | 287 | 16 |
The following players received entry into the singles main draw as wildcards:
The following players received entry into the singles main draw using protected rankings:
The following player received entry into the singles main draw as an alternate:
The following players received entry into the singles main draw using their ITF World Tennis Ranking:
The following players received entry from the qualifying draw:
The following player received entry as a lucky loser:
Mikael Torpegaard def. Nam Ji-sung 6–1, 7–5. Roberto Maytín / Jackson Withrow def. 
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