| 2019 Uruguay Open | |
|---|---|
| Date | 4–10 November |
| Edition | 15th |
| Surface | Clay |
| Location | Montevideo, Uruguay |
| Champions | |
| Singles | |
 Jaume Munar | |
| Doubles | |
 Facundo Bagnis / Andrés Molteni | |
The 2019 Uruguay Open was a professional tennis tournament played on clay courts. It was the fifteenth edition of the tournament which was part of the 2019 ATP Challenger Tour. It took place at the Carrasco Lawn Tennis Club in Montevideo, Uruguay between November 4 and 10, 2019.
| Country | Player | Rank1 | Seed |
|---|---|---|---|
 URU | Pablo Cuevas | 44 | 1 |
 BOL | Hugo Dellien | 76 | 2 |
| ARG | Federico Delbonis | 79 | 3 |
 BRA | Thiago Monteiro | 89 | 4 |
| ESP | Jaume Munar | 98 | 5 |
 SVK | Andrej Martin | 115 | 6 |
| ARG | Federico Coria | 121 | 7 |
| ARG | Facundo Bagnis | 138 | 8 |
 PER | Juan Pablo Varillas | 155 | 9 |
| ESP | Mario Vilella Martínez | 179 | 10 |
| SVK | Jozef Kovalík | 180 | 11 |
 GER | Yannick Hanfmann | 183 | 12 |
| BRA | João Menezes | 194 | 13 |
 POR | João Domingues | 196 | 14 |
| ARG | Facundo Mena | 200 | 15 |
| ARG | Andrea Collarini | 204 | 16 |
The following players received wildcards into the singles main draw:
The following players received entry into the singles main draw as alternates:
The following players received entry from the qualifying draw:
The following player received entry as a lucky loser:
Jaume Munar def. Federico Delbonis 7–5, 6–2. Facundo Bagnis / Andrés Molteni def. Orlando Luz / Rafael Matos 6–4, 5–7, [12–10].