| 2019 Zhuhai Open | |
|---|---|
| Date | 4–10 March |
| Edition | 4th |
| Category | ATP Challenger Tour |
| Surface | Hard |
| Location | Zhuhai, China |
| Champions | |
| Singles | |
 Enrique López Pérez | |
| Doubles | |
 Gong Maoxin / Zhang Ze | |
The 2019 Zhuhai Open was a professional tennis tournament played on hard courts. It was the fourth edition of the tournament and part of the 2019 ATP Challenger Tour. It took place in Zhuhai, China between 4 and 10 March 2019.
| Country | Player | Rank1 | Seed |
|---|---|---|---|
 CAN | Brayden Schnur | 107 | 1 |
 CYP | Marcos Baghdatis | 128 | 2 |
 GER | Oscar Otte | 156 | 3 |
 JPN | Hiroki Moriya | 173 | 4 |
 ISR | Dudi Sela | 182 | 5 |
| GER | Rudolf Molleker | 183 | 6 |
 KAZ | Aleksandr Nedovyesov | 191 | 7 |
| GER | Mats Moraing | 193 | 8 |
 AUT | Jurij Rodionov | 194 | 9 |
| CHN | Zhang Ze | 200 | 10 |
 SLO | Blaž Rola | 203 | 11 |
 AUS | Marc Polmans | 211 | 12 |
 CRO | Viktor Galović | 215 | 13 |
 EGY | Mohamed Safwat | 218 | 14 |
 ARG | Pedro Cachin | 236 | 15 |
 BRA | Guilherme Clezar | 237 | 16 |
The following players received wildcards into the singles main draw:
Gao Xin He Yecong Hua Runhao Xia Zihao Zhang Zhizhen The following players received entry into the singles main draw using their ITF World Tennis Ranking:
Javier Barranco Cosano 
Raúl Brancaccio 
Baptiste Crepatte Karim-Mohamed Maamoun The following players received entry from the qualifying draw:
Enrique López Pérez def. 
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