| 2019 Challenger Ciudad de Guayaquil | |
|---|---|
| Date | 28 October – 3 November |
| Edition | 15th |
| Surface | Clay |
| Location | Guayaquil, Ecuador |
| Champions | |
| Singles | |
 Thiago Seyboth Wild | |
| Doubles | |
 Ariel Behar /  Gonzalo Escobar | |
The 2019 Challenger Ciudad de Guayaquil was a professional tennis tournament played on clay courts. It was the fifteenth edition of the tournament which was part of the 2019 ATP Challenger Tour. It took place in Guayaquil, Ecuador between October 28 and November 3, 2019.
| Country | Player | Rank1 | Seed |
|---|---|---|---|
 BOL | Hugo Dellien | 78 | 1 |
 ARG | Leonardo Mayer | 95 | 2 |
 ESP | Jaume Munar | 96 | 3 |
| BRA | Thiago Monteiro | 97 | 4 |
 SVK | Andrej Martin | 115 | 5 |
 POR | Pedro Sousa | 116 | 6 |
 ITA | Paolo Lorenzi | 120 | 7 |
 IND | |||
| ARG | Federico Coria | 131 | 9 |
| ECU | Emilio Gómez | 143 | 10 |
| ARG | Facundo Bagnis | 146 | 11 |
 PER | Juan Pablo Varillas | 161 | 12 |
| SVK | Jozef Kovalík | 178 | 13 |
| ESP | Mario Vilella Martínez | 179 | 14 |
 GER | Yannick Hanfmann | 187 | 15 |
| POR | João Domingues | 188 | 16 |
The following players received wildcards into the singles main draw:
Hugo Dellien Facundo Díaz Acosta 
Alejandro González Antonio Cayetano March Alexander ZederbauerThe following player received entry into the singles main draw as an alternate:
Wilson LeiteThe following players received entry from the qualifying draw:
The following player received entry as a lucky loser:
Thiago Seyboth Wild def. Hugo Dellien 6–4, 6–0. Ariel Behar / Gonzalo Escobar def. Pedro Sakamoto / Thiago Seyboth Wild 7–6(7–4), 7–6(7–5).The 2015 Copa Fila was a professional tennis tournament played on clay courts. It was the fifth edition of the tournament which was part of the 2015 ATP Challenger Tour. It took place in Buenos Aires, Argentina between 9 and 15 November 2015.
The 2016 Campeonato Internacional de Tenis de Santos was a professional tennis tournament played on clay courts. It was the sixth edition of the tournament which was part of the 2016 ATP Challenger Tour. It took place in Santos, Brazil between 19 and 25 September 2016.
The 2017 Challenger Ciudad de Guayaquil was a professional tennis tournament played on clay courts. It was the thirteenth edition of the tournament which was part of the 2017 ATP Challenger Tour. It took place in Guayaquil, Ecuador between October 30 and November 4, 2017.
The 2017 Rio Tennis Classic was a professional tennis tournament played on clay courts. It was the first edition of the tournament which is part of the 2017 ATP Challenger Tour. It took place in Rio de Janeiro, Brazil from 20 to 26 November 2017.
Thiago Seyboth Wild is a Brazilian tennis player. He won 2018 US Open junior singles title. He reached a career high ATP singles ranking of No. 106 on September 14, 2020 and a career high ITF junior ranking of No. 8 on January 22, 2018. He also has a career high ATP doubles ranking of 393 achieved on February 10, 2020.
The 2018 Campeonato Internacional de Tênis de Campinas was a professional tennis tournament played on clay courts. It was the seventh edition of the tournament which was part of the 2018 ATP Challenger Tour. It took place in Campinas, Brazil between 1 and 7 October 2018.
The 2018 Challenger Ciudad de Guayaquil was a professional tennis tournament played on clay courts. It was the fourteenth edition of the tournament which was part of the 2018 ATP Challenger Tour. It took place in Guayaquil, Ecuador between October 29 and November 3, 2018.
The 2018 Uruguay Open was a professional tennis tournament played on clay courts. It was the fourteenth edition of the tournament which was part of the 2018 ATP Challenger Tour. It took place at the Carrasco Lawn Tennis Club in Montevideo, Uruguay between November 5 and 11, 2018.
The 2019 Rio Open was a professional men's tennis tournament played on outdoor clay courts. It was the sixth edition of the Rio Open, and formed part of the ATP Tour 500 series of the 2019 ATP Tour. It took place in Rio de Janeiro, Brazil between February 18 and 24, 2019.
The 2019 Córdoba Open was a men's tennis tournament played on outdoor clay courts. It was the 1st edition of the Córdoba Open, and part of the ATP Tour 250 series of the 2019 ATP Tour. It took place at the Estadio Mario Alberto Kempes in Córdoba, Argentina, from 4 February through 10 February 2019. Unseeded Juan Ignacio Londero, who entered on a wildcard, won the singles title.
The 2019 Brasil Open was a tennis tournament played on indoor clay courts. It was the 19th edition of the Brasil Open, and part of the ATP Tour 250 series of the 2019 ATP Tour. It took place from February 25 through March 3, 2019, in São Paulo, Brazil.
The 2019 Challenger ATP Cachantún Cup was a professional tennis tournament played on red clay courts. It was the 12th edition of the tournament which was part of the 2019 ATP Challenger Tour. It took place in Santiago, Chile between 4 and 10 March 2019.
The 2019 San Luis Open Challenger Tour was a professional tennis tournament played on hard courts. It was the 26th edition of the tournament which was part of the 2019 ATP Challenger Tour. It took place in San Luis Potosí, Mexico between 15 and 21 April 2019.
The 2019 Aspria Tennis Cup was a professional tennis tournament played on clay courts. It was the fourteenth edition of the tournament which was part of the 2019 ATP Challenger Tour. It took place in Milan, Italy between 24 and 30 June 2019.
The 2019 Challenger de Buenos Aires was a professional tennis tournament played on clay courts. It was the ninth edition of the tournament which was part of the 2019 ATP Challenger Tour. It took place in Buenos Aires, Argentina between 23 and 29 September 2019.
The 2020 Chile Open was a men's tennis tournament played on outdoor clay courts. It was the 22nd edition of the Chile Open, and part of the ATP 250 of the 2020 ATP Tour. It took place in Santiago, Chile from 24 February through 1 March 2020. Unseeded Thiago Seyboth Wild, who entered on a wildcard, won the singles title.
The 2020 Open du Pays d'Aix was a professional tennis tournament played on clay courts. It was the seventh edition of the tournament which was part of the 2020 ATP Challenger Tour. It took place in Aix-en-Provence, France between 7 and 13 September 2020.
The 2021 Córdoba Open was a men's tennis tournament played on outdoor clay courts. It was the third edition of the Córdoba Open, and part of the ATP Tour 250 series of the 2021 ATP Tour. It took place at the Estadio Mario Alberto Kempes in Córdoba, Argentina, from 20 February until 28 February 2021.
The 2021 ATP Lyon Open was a men's tennis tournament played on outdoor clay courts. It was the fourth edition of the Lyon Open and part of the ATP Tour 250 series of the 2021 ATP Tour. It took place in the city of Lyon, France, from 15 May through 22 May 2021.
The 2021 Lima Challenger was a professional tennis tournament played on clay courts. It was the fifteenth edition of the tournament which was part of the 2021 ATP Challenger Tour. It took place in Lima, Peru between 27 September and 3 October 2021.