| 2019 Prosperita Open | |
|---|---|
| Date | 29 April – 5 May |
| Edition | 16th |
| Draw | 48S / 16D |
| Surface | Clay |
| Location | Ostrava, Czech Republic |
| Champions | |
| Singles | |
 Kamil Majchrzak | |
| Doubles | |
 Luca Margaroli /  Filip Polášek | |
The 2019 Prosperita Open was a professional tennis tournament played on clay courts. It was the 16th edition of the tournament which was part of the 2019 ATP Challenger Tour. It took place in Ostrava, Czech Republic between 29 April and 5 May.
| Country | Player | Rank1 | Seed |
|---|---|---|---|
 RSA | Lloyd Harris | 90 | 1 |
 CZE | Jiří Veselý | 94 | 2 |
 ESP | Marcel Granollers | 110 | 3 |
| POL | Kamil Majchrzak | 121 | 4 |
 AUT | Dennis Novak | 122 | 5 |
 ITA | Stefano Travaglia | 154 | 6 |
 EST | Jürgen Zopp | 177 | 7 |
 BEL | Arthur De Greef | 179 | 8 |
 GER | Dominik Köpfer | 183 | 9 |
| ITA | Stefano Napolitano | 189 | 10 |
 NED | Tallon Griekspoor | 192 | 11 |
 CRO | Viktor Galović | 198 | 12 |
| CZE | Adam Pavlásek | 208 | 13 |
| SVK | Norbert Gombos | 222 | 14 |
| NED | Thiemo de Bakker | 225 | 15 |
| ITA | Matteo Viola | 230 | 16 |
The following players received wildcards into the singles main draw:
Marek Gengel Jiří Lehečka Tomáš Macháč David Poljak Dalibor Svrčina The following player received entry into the singles main draw using a protected ranking:
The following player received entry into the singles main draw as an alternate:
The following players received entry into the singles main draw using their ITF World Tennis Ranking:
Riccardo Bonadio 
Ivan Gakhov Peter Heller Vít Kopřiva Alexander Zhurbin The following players received entry from the qualifying draw:
Kamil Majchrzak def. Jannik Sinner 6–1, 6–0. Luca Margaroli / Filip Polášek def. Thiemo de Bakker / Tallon Griekspoor 6–4, 2–6, [10–8].