| 2025 Challenger La Manche | |
|---|---|
| Date | 10–16 March |
| Edition | 32nd |
| Surface | Hard (indoor) |
| Location | Cherbourg, France |
| 2024 Champions | |
| Singles | |
 Zsombor Piros | |
| Doubles | |
 George Goldhoff /  James Trotter | |
The 2025 Challenger La Manche was a professional tennis tournament played on indoor hard courts. It was the 32nd edition of the tournament which was part of the 2025 ATP Challenger Tour. It took place in Cherbourg, France between 10 and 16 March 2025.
| Country | Player | Rank1 | Seed |
|---|---|---|---|
 FRA | Pierre-Hugues Herbert | 180 | 1 |
| Alibek Kachmazov | 186 | 2 | |
| FRA | |||
| JPN | Yuta Shimizu | 197 | 4 |
| FRA | Antoine Escoffier | 206 | 5 |
 AUT | Jurij Rodionov | 209 | 6 |
 BEL | Gauthier Onclin | 212 | 7 |
 KAZ | Beibit Zhukayev | 213 | 8 |
The following players received wildcards into the singles main draw:
Kenny de Schepper Maé Malige Loann MassardThe following player received entry into the singles main draw as an alternate:
The following players received entry from the qualifying draw:
The following players received entry as lucky losers:
vs. / vs. / 