| 2025 Garden Open | |
|---|---|
| Date | 21 – 27 April |
| Edition | 17th |
| Surface | Clay |
| Location | Rome, Italy |
| Champions | |
| Singles | |
 Matteo Gigante | |
| Doubles | |
 Erik Grevelius / Adam Heinonen | |
The 2025 Roma Garden Open was a professional tennis tournament played on clay courts. It was the 17th edition of the tournament which was part of the 2025 ATP Challenger Tour. It took place in Rome, Italy between 21 and 27 April 2025.
| Country | Player | Rank1 | Seed |
|---|---|---|---|
 LTU | Vilius Gaubas | 144 | 1 |
 CRO | Duje Ajduković | 170 | 2 |
 LIB | Hady Habib | 178 | 3 |
 KAZ | Timofey Skatov | 179 | 4 |
 AUT | Lukas Neumayer | 195 | 5 |
 FRA | Arthur Bouquier | 199 | 6 |
| ITA | Matteo Gigante | 200 | 7 |
| ITA | Federico Arnaboldi | 204 | 8 |
The following players received wildcards into the singles main draw:
Lorenzo Carboni Gabriele Pennaforti Jacopo Vasamì The following players received entry into the singles main draw as alternates:
The following players received entry from the qualifying draw:
Mika Brunold 
Kimmer Coppejans Sandro Kopp
Lukáš Pokorný
Oleg Prihodko Stefano Travaglia Matteo Gigante def. Vilius Gaubas 6–2, 3–6, 6–4. Erik Grevelius / Adam Heinonen def. Marco Bortolotti / Giorgio Ricca 7–6(7–2), 7–5.