| 2025 Serve First Open | |
|---|---|
| Date | 12–17 August |
| Edition | 1st |
| Surface | Hard |
| Location | Sumter, South Carolina, United States |
| Champions | |
| Singles | |
 Mattia Bellucci | |
| Doubles | |
 Ryan Seggerman / Patrik Trhac | |
The 2025 Serve First Open was a professional tennis tournament played on hardcourts. It was the first edition of the tournament which was part of the 2025 ATP Challenger Tour. It took place in Sumter, South Carolina, United States between 12 and 17 August 2025. [1]
| Country | Player | Rank1 | Seed |
|---|---|---|---|
 BEL | Zizou Bergs | 54 | 1 |
 JPN | |||
| ITA | Mattia Bellucci | 74 | 3 |
 AUT | Filip Misolic | 96 | 4 |
 KAZ | Alexander Shevchenko | 102 | 5 |
 GEO | Nikoloz Basilashvili | 112 | 6 |
| JPN | Shintaro Mochizuki | 120 | 7 |
 SVK | Lukáš Klein | 122 | 8 |
 POR | Jaime Faria | 124 | 9 |
The following players received wildcards into the singles main draw:
The following players received entry into the singles main draw as alternates:
The following players received entry from the qualifying draw:
The following players received entry as lucky losers:
Strong Kirchheimer Karl Poling Mattia Bellucci def. Alexander Shevchenko 7–6(7–5), 3–1 ret. Ryan Seggerman / Patrik Trhac def. 
Sriram Balaji / Rithvik Choudary Bollipalli 6–4, 7–6(7–3).
