| 2025 Open de Oeiras | |
|---|---|
| Date | 14–20 April |
| Edition | 12th |
| Surface | Clay |
| Location | Oeiras, Portugal |
| Champions | |
| Singles | |
 Elmer Møller | |
| Doubles | |
 Karol Drzewiecki / Piotr Matuszewski | |
The 2025 Open de Oeiras was a professional tennis tournament played on clay courts. It was the 12th edition of the tournament which was part of the 2025 ATP Challenger Tour. It took place in Oeiras, Portugal between 14 and 20 April 2025.
| Country | Player | Rank1 | Seed |
|---|---|---|---|
 ARG | Francisco Comesaña | 61 | 1 |
| Roman Safiullin | 68 | 2 | |
 BEL | Raphaël Collignon | 91 | 3 |
 BRA | Thiago Monteiro | 94 | 4 |
 USA | |||
 SRB | Dušan Lajović | 109 | 6 |
| BRA | Thiago Seyboth Wild | 111 | 7 |
 FRA | Valentin Royer | 116 | 8 |
The following players received wildcards into the singles main draw:
Pedro Araújo Gastão Elias Tiago PereiraThe following players received entry into the singles main draw as alternates:
The following players received entry from the qualifying draw:
Rémy Bertola Juan Manuel Cerúndolo 
Guy den Ouden 
Stefano Travaglia 
Denis Yevseyev 
Bernabé Zapata Miralles The following player received entry as a lucky loser:
Elmer Møller def. Francisco Comesaña 6–0, 6–4. Karol Drzewiecki / Piotr Matuszewski def. Francisco Cabral / 
Lucas Miedler 6–4, 3–6, [10–8].