| 2025 Upper Austria Open | |
|---|---|
| Date | 28 April – 4 May |
| Edition | 4th |
| Surface | Clay |
| Location | Mauthausen, Austria |
| Champions | |
| Singles | |
 Cristian Garín | |
| Doubles | |
 Nico Hipfl /  Jérôme Kym | |
The 2025 Danube Upper Austria Open powered by SKE was a professional tennis tournament played on clay courts. It was the fourth edition of the tournament which was part of the 2025 ATP Challenger Tour. It took place in Mauthausen, Austria between 28 April and 4 May 2025.
| Country | Player | Rank1 | Seed |
|---|---|---|---|
 BEL | |||
 BRA | Thiago Monteiro | 94 | 2 |
 CRO | Marin Čilić | 109 | 3 |
 ITA | Fabio Fognini | 112 | 4 |
| CHI | Tomás Barrios Vera | 128 | 5 |
 JPN | Taro Daniel | 131 | 6 |
| SUI | Jérôme Kym | 133 | 7 |
 ARG | Thiago Agustín Tirante | 134 | 8 |
The following players received wildcards into the singles main draw:
The following player received entry into the singles main draw as a special exempt:
The following player received entry into the singles main draw through the Next Gen Accelerator programme:
The following player received entry into the singles main draw as an alternate:
The following players received entry from the qualifying draw:
Mika Brunold 
Dimitar Kuzmanov 
Tadeáš Paroulek Jakub Paul David Pichler Thiago Seyboth Wild The following player received entry as a lucky loser:
Cristian Garín def. Tomás Barrios Vera 3–6, 6–1, 6–4. Nico Hipfl / Jérôme Kym def. 
Ryan Seggerman / 
David Stevenson 7–5, 3–6, [10–2].
