| 2025 Wuxi Open | |
|---|---|
| Date | 5–11 May |
| Edition | 2nd |
| Surface | Hard |
| Location | Wuxi, China |
| Champions | |
| Singles | |
 Sun Fajing | |
| Doubles | |
 Vasil Kirkov /  Bart Stevens | |
The 2025 Wuxi Open was a professional tennis tournament played on hard courts. It was the second edition of the tournament which was part of the 2025 ATP Challenger Tour. It took place in Wuxi, China between 5 and 11 May 2025.
| Country | Player | Rank1 | Seed |
|---|---|---|---|
 AUS | Adam Walton | 86 | 1 |
| AUS | Tristan Schoolkate | 122 | 2 |
 FRA | Térence Atmane | 136 | 3 |
| AUS | Li Tu | 164 | 4 |
| FRA | Hugo Grenier | 175 | 5 |
| AUS | James McCabe | 176 | 6 |
| FRA | Constant Lestienne | 180 | 7 |
| Alibek Kachmazov | 185 | 8 |
The following players received wildcards into the singles main draw:
The following player received entry into the singles main draw using a protected ranking:
The following players received entry from the qualifying draw:
Moerani Bouzige Andre Ilagan
Shintaro Imai Li Zhe Yusuke Takahashi Evan Zhu Sun Fajing def. Alex Bolt 7–6(7–4), 6–4. Vasil Kirkov / Bart Stevens def. 
Ray Ho / Matthew Romios 3–6, 7–5, [10–6].