3,3-Diphenylpropylamine

Last updated
3,3-Diphenylpropylamine
3,3-diphenylpropylamine.svg
Names
Preferred IUPAC name
3,3-Diphenylpropan-1-amine
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
ECHA InfoCard 100.024.532 OOjs UI icon edit-ltr-progressive.svg
PubChem CID
UNII
  • InChI=1S/C15H17N/c16-12-11-15(13-7-3-1-4-8-13)14-9-5-2-6-10-14/h1-10,15H,11-12,16H2 Yes check.svgY
    Key: KISZTEOELCMZPY-UHFFFAOYSA-N Yes check.svgY
  • C1=CC=C(C=C1)C(CCN)C2=CC=CC=C2
Properties
C15H17N
Molar mass 211.308 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
X mark.svgN  verify  (what is  Yes check.svgYX mark.svgN ?)

3,3-Diphenylpropylamine is a form of diphenylpropylamine.

It is commonly conjugated to another agent giving a "bifunctional" molecule. Such agents are not infrequently used to treat Cardiovascular disease (CVD).

Further embellishment of the molecular structure can lead to an agent that is called Delucemine.

3,3-Diphenylpropylamine derivatives list table
NameIdentifierPicture
BIIA 0388 CID:9958467 [337359-07-6] BIIA 0388.svg
BZP derivative [1] 3,3-Diphenylpropylamine-BZP.svg
Droprenilamine [57653-27-7] Droprenilamine.svg
Fendiline [13042-18-7]
Lercanidipine [100427-26-7]
KD-983 [50597-65-4] KD-983.svg
Mepramidil [23891-60-3] Mepramidil.svg
Milverine [75437-14-8] Milverine.svg
PF 244 Fb: [52017-07-9] PF 244.svg
Prenylamine [390-64-7]
SoRI-20041 now SRI-20041
Tiopropamine [39516-21-7] Tiopropamine.svg
[117-34-0] [5586-73-2] amide: (117-34-0) (5586-73-2) amide.svg
[117-34-0] [5586-73-2] amide:

Related Research Articles

<span class="mw-page-title-main">Agent Orange</span> Herbicide used by the US in the Vietnam War

Agent Orange is a chemical herbicide and defoliant, one of the tactical use Rainbow Herbicides.

Nerve agents, sometimes also called nerve gases, are a class of organic chemicals that disrupt the mechanisms by which nerves transfer messages to organs. The disruption is caused by the blocking of acetylcholinesterase (AChE), an enzyme that catalyzes the breakdown of acetylcholine, a neurotransmitter. Nerve agents are irreversible acetylcholinesterase inhibitors used as poison.

<span class="mw-page-title-main">Bounty hunter</span> Person who catches fugitives for a monetary reward

A bounty hunter is a private agent working for a bail bondsman who captures fugitives or criminals for a commission or bounty. The occupation, officially known as a bail enforcement agent or fugitive recovery agent, has traditionally operated outside the legal constraints that govern police officers and other agents of the state. This is because a bail agreement between a defendant and a bail bondsman is essentially a civil contract that is incumbent upon the bondsman to enforce. Since they are not police officers, bounty hunters are exposed to legal liabilities from which agents of the state are protected as these immunities enable police to perform their functions effectively without fear of lawsuits. Everyday citizens approached by a bounty hunter are neither required to answer their questions nor allowed to be detained. Bounty hunters are typically independent contractors paid a commission of the total bail amount that is owed by the fugitive; they provide their own professional liability insurance and only get paid if they are able to find the "skip" and bring them in.

<span class="mw-page-title-main">Mechanism design</span> Field in game theory

Mechanism design is a field in economics and game theory that takes an objectives-first approach to designing economic mechanisms or incentives, toward desired objectives, in strategic settings, where players act rationally. Because it starts at the end of the game, then goes backwards, it is also called reverse game theory. It has broad applications, from economics and politics in fields such as market design, auction theory and social choice theory to networked-systems.

An agent-based model (ABM) is a computational model for simulating the actions and interactions of autonomous agents in order to understand the behavior of a system and what governs its outcomes. It combines elements of game theory, complex systems, emergence, computational sociology, multi-agent systems, and evolutionary programming. Monte Carlo methods are used to understand the stochasticity of these models. Particularly within ecology, ABMs are also called individual-based models (IBMs). A review of recent literature on individual-based models, agent-based models, and multiagent systems shows that ABMs are used in many scientific domains including biology, ecology and social science. Agent-based modeling is related to, but distinct from, the concept of multi-agent systems or multi-agent simulation in that the goal of ABM is to search for explanatory insight into the collective behavior of agents obeying simple rules, typically in natural systems, rather than in designing agents or solving specific practical or engineering problems.

<span class="mw-page-title-main">National Forests Office (France)</span> French institution that manages public forests

The National Forests Office, or ONF, is a Government of France agency that manages the state forests, city forests and biological reserves. ONF is based in Paris.

<span class="mw-page-title-main">No. 161 Squadron RAF</span> Defunct flying squadron of the Royal Air Force

No. 161 Squadron was a highly secretive unit of the Royal Air Force, performing missions as part of the Royal Air Force Special Duties Service. It was tasked with missions of the Special Operations Executive (SOE) and the Secret Intelligence Service (SIS) during the Second World War. Their primary role was to drop and collect secret agents and equipment into and from Nazi-occupied Europe. The squadron had a secondary role in acting as the King's Flight.

Broken Ways is a 1913 American short silent Western film directed by D. W. Griffith, starring Henry B. Walthall and Blanche Sweet. A print of the film survives.

<span class="mw-page-title-main">Levomoramide</span> Chemical compound

Levomoramide is the inactive isomer of the opioid analgesic dextromoramide, invented by the chemist Paul Janssen in 1956. Unlike dextromoramide, which is a potent analgesic with high abuse potential, levomoramide is virtually without activity.

<span class="mw-page-title-main">IC-26</span> Chemical compound

IC-26 is an analogue of the opioid analgesic methadone, where the carbonyl group has been replaced by the bioisosteric sulfone group.

<span class="mw-page-title-main">VR (nerve agent)</span> Chemical compound

VR is a "V-series" unitary nerve agent closely related to the better-known VX nerve agent. It became a prototype for the series of Novichok agents. According to chemical weapons expert Jonathan Tucker, the first binary formulation developed under the Soviet Foliant program was used to make Substance 33, differing from VX only in the alkyl substituents on its nitrogen and oxygen atoms. "This weapon was given the code name Novichok."

<span class="mw-page-title-main">Octatropine methylbromide</span> Pharmaceutical drug

Octatropine methylbromide (INN) or anisotropine methylbromide (USAN), trade names Valpin, Endovalpin, Lytispasm and others, is a muscarinic antagonist and antispasmodic. It was introduced to the U.S. market in 1963 as an adjunct in the treatment of peptic ulcer, and promoted as being more specific to the gastrointestinal tract than other anticholinergics, although its selectivity was questioned in later studies.

<span class="mw-page-title-main">2009 Major League Baseball draft</span> Baseball draft of amateur players by Major League Baseball

The 2009 Major League Baseball draft was held June 9 to June 11 at the MLB Network Studios in Secaucus, New Jersey.

<span class="mw-page-title-main">Trimethyldiphenylpropylamine</span> Chemical compound

Trimethyldiphenylpropylamine (N,N,1-Trimethyl-3,3-diphenylpropylamine) is a drug used for functional gastrointestinal disorders. Its tradename is Recipavrin.

A hypomethylating agent is a drug that inhibits DNA methylation: the modification of DNA nucleotides by addition of a methyl group. Because DNA methylation affects cellular function through successive generations of cells without changing the underlying DNA sequence, treatment with a hypomethylating agent is considered a type of epigenetic therapy.

Diphenylpropylamine is a propylamine derivative and may refer to:

The molecular formula C15H17N (molar mass: 211.30 g/mol, exact mass: 211.1361 u) may refer to:

<span class="mw-page-title-main">Plomestane</span> Chemical compound

Plomestane is a steroidal, irreversible aromatase inhibitor which was under development by Marion Merrell Dow/Hoechst Marion Russell as an antineoplastic agent for the treatment of breast cancer. It was found to be effective in preclinical studies and was also found to produce few adverse effects in human clinical trials, significantly reducing estrogen levels with a single administration. However, development of the drug for clinical use was halted due to "technical issues" and it was never marketed.

<span class="mw-page-title-main">GP (nerve agent)</span> Chemical compound

GP is an organophosphate nerve agent of the G-series, with a relatively slow rate of hydrolysis, and thus high stability and persistence in the environment.

OPA is a mixture of isopropyl alcohol and isopropylamine that is used in the production of the sarin nerve agent. The mixture reacts with methylphosphonyl difluoride to produce sarin.

References

  1. Tadayuki Suzuki & Toshiharu Megumi, U.S. Patent 3,957,790 (1976 to Tokyo Tanabe Co Ltd).
  2. Urbani, P., Cascio, M. G., Ramunno, A., Bisogno, T., Saturnino, C., Marzo, V. D. (August 2008). "Novel sterically hindered cannabinoid CB1 receptor ligands". Bioorganic & Medicinal Chemistry. 16 (15): 7510–7515. doi:10.1016/j.bmc.2008.06.001. hdl: 11563/122572 . PMID   18579386.