Alanine transaminase (ALT) is a transaminase enzyme. It is also called alanine aminotransferase and was formerly called serum glutamate-pyruvate transaminase or serum glutamic-pyruvic transaminase (SGPT) and was first characterized in the mid-1950s by Arthur Karmen and colleagues. ALT is found in plasma and in various body tissues but is most common in the liver. It catalyzes the two parts of the alanine cycle. Serum ALT level, serum AST level, and their ratio are commonly measured clinically as biomarkers for liver health. The tests are part of blood panels.
Transaminases or aminotransferases are enzymes that catalyze a transamination reaction between an amino acid and an α-keto acid. They are important in the synthesis of amino acids, which form proteins.
The branched-chain α-ketoacid dehydrogenase complex is a multi-subunit complex of enzymes that is found on the mitochondrial inner membrane. This enzyme complex catalyzes the oxidative decarboxylation of branched, short-chain alpha-ketoacids. BCKDC is a member of the mitochondrial α-ketoacid dehydrogenase complex family comprising pyruvate dehydrogenase and alpha-ketoglutarate dehydrogenase, key enzymes that function in the Krebs cycle.
In enzymology, a 2-oxoaldehyde dehydrogenase (NAD+) (EC 1.2.1.23) is an enzyme that catalyzes the chemical reaction
The enzyme 2,2-dialkylglycine decarboxylase (pyruvate) (EC 4.1.1.64) catalyzes the chemical reaction
In enzymology, a 1D-1-guanidino-3-amino-1,3-dideoxy-scyllo-inositol transaminase is an enzyme that catalyzes the chemical reaction
In enzymology, 4-aminobutyrate transaminase, also called GABA transaminase or 4-aminobutyrate aminotransferase, or GABA-T, is an enzyme that catalyzes the chemical reaction:
In enzymology, an adenosylmethionine-8-amino-7-oxononanoate transaminase is an enzyme that catalyzes the chemical reaction
In enzymology, an alanine-glyoxylate transaminase is an enzyme that catalyzes the chemical reaction
In enzymology, an aminolevulinate transaminase is an enzyme that catalyzes the chemical reaction
In enzymology, an aromatic-amino-acid transaminase is an enzyme that catalyzes the chemical reaction
In enzymology, an asparagine-oxo-acid transaminase is an enzyme that catalyzes the chemical reaction
In enzymology, a beta-alanine-pyruvate transaminase is an enzyme that catalyzes the chemical reaction
In enzymology, a D-amino-acid transaminase is an enzyme that catalyzes the chemical reaction:
In enzymology, a diaminobutyrate-pyruvate transaminase is an enzyme that catalyzes the chemical reaction
In enzymology, a dTDP-4-amino-4,6-dideoxy-D-glucose transaminase is an enzyme that catalyzes the chemical reaction
In enzymology, a glutamine-pyruvate transaminase is an enzyme that catalyzes the chemical reaction
In enzymology, a (R)-3-amino-2-methylpropionate—pyruvate transaminase is an enzyme that catalyzes the chemical reaction
In enzymology, a serine-pyruvate transaminase is an enzyme that catalyzes the chemical reaction
In enzymology, a valine-pyruvate transaminase is an enzyme that catalyzes the chemical reaction
