Anethole trithione

Anethole trithione

Clinical data
ATC code	A16AX02 ( WHO )
Identifiers
IUPAC name 5-(4-methoxyphenyl)-3H-1,2-dithiole-3-thione
CAS Number	532-11-6  Y
PubChem CID	2194
DrugBank	DB13853  N
ChemSpider	2109  Y
UNII	QUY32964DJ
KEGG	D01584  Y
ChEMBL	ChEMBL178862  Y
CompTox Dashboard (EPA)	DTXSID9046651
ECHA InfoCard	100.007.754
Chemical and physical data
Formula	C10H8OS3
Molar mass	240.35 g·mol−1
3D model (JSmol)	Interactive image
SMILES S=C\2SS/C(c1ccc(OC)cc1)=C/2
InChI InChI=1S/C10H8OS3/c1-11-8-4-2-7(3-5-8)9-6-10(12)14-13-9/h2-6H,1H3 Y Key:KYLIZBIRMBGUOP-UHFFFAOYSA-N Y
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Anethole trithione, anetholtrithione, or anetholtrithion (JAN) is a drug used in the treatment of dry mouth. It is listed in the U.S. National Cancer Institute's Dictionary of Cancer Terms as being studied in the treatment of cancer. ^[1] Anethole trithione is an organosulfur compound, specifically, a dithiole-thione derivative. ^[2]

Brand names

• Felviten
• Halpen
• Hepasulfol - Franco-Indian Pharmaceuticals
• Heporal
• Mucinol - Sanofi-Aventis
• Sialor - Paladin Laboratories; Pharmascience; Solvay; Zuoz Pharma
• Sonicur - Solvay
• Sulfarlem - Solvay; Aguettant; Edward Keller; Sanofi-Aventis
• Sulfarlem S - EG Labo
• Tiopropen
• Tiotrifar

See also

• Anethole

References

1. Anetholtrithione entry in the public domain NCI Dictionary of Cancer Terms. Retrieved September 13, 2008.
2. Christen MO (1995). "Anethole dithiolethione: Biochemical considerations". Biothiols Part B: Glutathione and Thioredoxin: Thiols in Signal Transduction and Gene Regulation. Methods in Enzymology. Vol. 252. pp. 316–23. doi:10.1016/0076-6879(95)52034-1. ISBN   9780121821531. PMID   7476368.