St. Peter's Church is a Roman Catholic parish church in the inner city of Munich, southern Germany. Its 91-metre (299 ft) tower is commonly known as "Alter Peter"—Old Peter—and is emblematic of Munich. St Peter's is the oldest recorded parish church in Munich and presumably the originating point for the whole city.
Kružná is a village and municipality in the Rožňava District in the Košice Region of middle-eastern Slovakia.
Rakovnica is a village and municipality in the Rožňava District in the Košice Region of middle-eastern Slovakia.
Epithelial cell adhesion molecule (EpCAM), also known as CD326 among other names, is a transmembrane glycoprotein mediating Ca2+-independent homotypic cell–cell adhesion in epithelia. EpCAM is also involved in cell signaling, migration, proliferation, and differentiation. Additionally, EpCAM has oncogenic potential via its capacity to upregulate c-myc, e-fabp, and cyclins A & E. Since EpCAM is expressed exclusively in epithelia and epithelial-derived neoplasms, EpCAM can be used as diagnostic marker for various cancers. It appears to play a role in tumorigenesis and metastasis of carcinomas, so it can also act as a potential prognostic marker and as a potential target for immunotherapeutic strategies.
Matrix metalloproteinase-26 also known as matrilysin-2 and endometase is an enzyme that in humans is encoded by the MMP26 gene.
Kallikrein-8 is a protein that in humans is encoded by the KLK8 gene.
Eukaryotic translation initiation factor 3 subunit J (eIF3j) is a protein that in humans is encoded by the EIF3J gene.
Cullin-7 is a RING-E3 ligase protein that in humans is encoded by the CUL7 gene.
Maternal embryonic leucine zipper kinase (MELK) is an enzyme that in humans is encoded by the MELK gene. MELK is a serine/threonine kinase belonging to the family of AMPK/Snf1 protein kinases. MELK was first identified present as maternal mRNA in mouse embryos. MELK expression is elevated in a number of cancers and is an active research target for pharmacological inhibition.
Serine/threonine-protein kinase Pim-2 is an enzyme that in humans is encoded by the PIM2 gene. The enzyme is a serine/threonine kinase that has roles in cell growth, proliferation, apoptosis, and regulation of signal transduction cascades.
The TUM Institute for Advanced Study (TUM-IAS) is a scientific institution of the Technische Universität München, conducting research in science, engineering and humanities. Its building is located on its Garching campus.
The Maine River is a short river in Washington County, Maine. From the outlet of Pocomoonshine Lake in Princeton, it runs 5.5 miles (8.9 km) southwest to Crawford Lake in Plantation No. 21. The outlet of Crawford Lake is the East Machias River, flowing to Machias Bay.
SCH-5472. is a stimulant drug developed by Schering-Plough in the 1950s.
The Salles des Croisades is a set of rooms located in the north wing of the Palace of Versailles.
In molecular biology, the miR-200 microRNA is a short RNA molecule. MicroRNAs function to regulate the expression levels of other genes by binding and cleaving mRNAs or inhibiting translation. The miR-200 family contains miR-200a, miR-200b, miR-200c, miR-141, and miR-429. There is growing evidence to suggest that miR-200 microRNAs are involved in cancer metastasis.
In molecular biology miR-205 microRNA is a short RNA molecule. MicroRNAs function to regulate the expression levels of other genes by several mechanisms. They are involved in numerous cellular processes, including development, proliferation, and apoptosis. Currently, it is believed that miRNAs elicit their effect by silencing the expression of target genes.
EPI-001 is the first inhibitor of the androgen receptor amino-terminal domain. The single stereoisomer of EPI-001, EPI-002, is a first-in-class drug that the USAN council assigned a new stem class "-aniten" and the generic name "ralaniten". This distinguishes the anitens novel molecular mechanism from anti androgens that bind the C-terminus ligand-binding domain and have the stem class "lutamide". EPI-001 and its stereoisomers and analogues were discovered by Marianne Sadar and Raymond Andersen, who co-founded the pharmaceutical company ESSA Pharma Inc for the clinical development of anitens for the treatment of castration-resistant prostate cancer (CRPC).
Lozier is a ghost town in Woodbury County, in the U.S. state of Iowa.
The Beer and Oktoberfest Museum in Munich deals with the history of beer and the Munich Oktoberfest.
The Hurd–Mori 1,2,3-thiadiazole synthesis is a name reaction in organic chemistry that allows for the generation of 1,2,3-thiadiazoles through the reaction of hydrazone derivatives with an N-acyl or N-tosyl group reacted with thionyl chloride. An analogous reaction gives 1,2,3-selenadiazoles by using selenium dioxide instead of thionyl chloride.
