Vrbovka is a municipality (village) in southern Slovakia. The nearest town is Veľký Krtíš. First written reference is from 1327.
St. Peter's Church is a Roman Catholic parish church in the inner city of Munich, southern Germany. Its 91-metre (299 ft) tower is commonly known as "Alter Peter"—Old Peter—and is emblematic of Munich. St Peter's is the oldest recorded parish church in Munich and presumably the originating point for the whole city.
Hucín is a village and municipality in Revúca District in the Banská Bystrica Region of Slovakia.
Kružná is a village and municipality in the Rožňava District in the Košice Region of middle-eastern Slovakia.
Rakovnica is a village and municipality in the Rožňava District in the Košice Region of middle-eastern Slovakia.
Plavé Vozokany is a village and municipality in the Levice District in the Nitra Region of Slovakia.
Volkovce is a village and municipality in Zlaté Moravce District of the Nitra Region, in western-central Slovakia.
Epithelial cell adhesion molecule (EpCAM), also known as CD326 among other names, is a transmembrane glycoprotein mediating Ca2+-independent homotypic cell–cell adhesion in epithelia. EpCAM is also involved in cell signaling, migration, proliferation, and differentiation. Additionally, EpCAM has oncogenic potential via its capacity to upregulate c-myc, e-fabp, and cyclins A & E. Since EpCAM is expressed exclusively in epithelia and epithelial-derived neoplasms, EpCAM can be used as diagnostic marker for various cancers. It appears to play a role in tumorigenesis and metastasis of carcinomas, so it can also act as a potential prognostic marker and as a potential target for immunotherapeutic strategies.
Matrix metalloproteinase-26 also known as matrilysin-2 and endometase is an enzyme that in humans is encoded by the MMP26 gene.
Kallikrein-8 is a protein that in humans is encoded by the KLK8 gene.
Cullin-7 is a RING-E3 ligase protein that in humans is encoded by the CUL7 gene.
Serine/threonine-protein kinase Pim-2 is an enzyme that in humans is encoded by the PIM2.
The Maine River is a short river in Washington County, Maine. From the outlet of Pocomoonshine Lake in Princeton, it runs 5.5 miles (8.9 km) southwest to Crawford Lake in Plantation No. 21. The outlet of Crawford Lake is the East Machias River, flowing to Machias Bay.
SCH-5472. is a stimulant drug developed by Schering-Plough in the 1950s.
Colle Marmo is a frazione of Bisenti in the Province of Teramo in the Abruzzo region of Italy.
In molecular biology, the miR-200 microRNA is a short RNA molecule. MicroRNAs function to regulate the expression levels of other genes by binding and cleaving mRNAs or inhibiting translation. The miR-200 family contains miR-200a, miR-200b, miR-200c, miR-141, and miR-429. There is growing evidence to suggest that miR-200 microRNAs are involved in cancer metastasis.
In molecular biology miR-205 microRNA is a short RNA molecule. MicroRNAs function to regulate the expression levels of other genes by several mechanisms. They are involved in numerous cellular processes, including development, proliferation, and apoptosis. Currently, it is believed that miRNAs elicit their effect by silencing the expression of target genes.
The Baroncelli Chapel is a chapel located at the end of the right transept in church of Santa Croce, central Florence, Italy.
Hisarköy is a village in the District of Ulus, Bartın Province, Turkey. As of 2010 it had a population of 545 people.
EPI-001 is the first inhibitor of the androgen receptor amino-terminal domain. The single stereoisomer of EPI-001, EPI-002, is a first-in-class drug that the USAN council assigned a new stem class "-aniten" and the generic name "ralaniten". This distinguishes the anitens novel molecular mechanism from anti androgens that bind the C-terminus ligand-binding domain and have the stem class "lutamide". EPI-001 and its stereoisomers and analogues were discovered by Marianne Sadar and Raymond Andersen, who co-founded the pharmaceutical company ESSA Pharma Inc for the clinical development of anitens for the treatment of castration-resistant prostate cancer (CRPC).
