Discodermia

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Discodermia
Discodermia ramifera (10.7717-peerj.8703) Figure 2 (cropped).png
Discodermia ramifera
Scientific classification Red Pencil Icon.png
Kingdom: Animalia
Phylum: Porifera
Class: Demospongiae
Order: Tetractinellida
Family: Theonellidae
Genus: Discodermia
du Bocage, 1869 [1]
Synonyms
  • CollinellaSchmidt, 1879
  • DesmahabanaAlcolado & Gotera, 1986

Discodermia is a genus of deep-water sea sponge. [1] [2]

Contents

Species

The following species are accepted within Discodermia: [1]

Pharmacology

Discodermins B-D Discodermin B-D.png
Discodermins B-D

D. dissoluta is of interest to bio and organic chemists because it produces (+)-discodermolide, a polyketide natural product with immunosuppressive and cancer killing properties. [3]

Antimicrobial/anticancer peptides called discodermins have been isolated from D. kiiensis. [4]

Related Research Articles

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Discodermia dissoluta is a deep-water sea sponge found in the Eastern, Southern, and Southwestern Caribbean, and in the Greater Antilles.

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References

  1. 1 2 3 "Discodermia". WoRMS. World Register of Marine Species . Retrieved 12 Sep 2020.
  2. Brück WM, Sennett SH, Pomponi SA, Willenz P, McCarthy PJ (2008). "Identification of the bacterial symbiont Entotheonella sp. in the mesohyl of the marine sponge Discodermia sp". The ISME Journal. 2 (3): 335–339. doi: 10.1038/ismej.2007.91 . PMID   18256706.
  3. Singh R, Sharma M, Joshi P, Rawat DS (2008). "Clinical status of anti-cancer agents derived from marine sources". Anti-Cancer Agents in Medicinal Chemistry. 8 (6): 603–617. doi:10.2174/187152008785133074. PMID   18690825.
  4. Otero-González, AJ; Magalhaes, BS; Garcia-Villarino, M; Lopez-Abarrategui, C; Sousa, DA; Dias, SC; Franco, OL (2010). "Antimicrobial peptides from marine invertebrates as a new frontier for microbial infection control". FASEB Journal. 24 (5): 1320–34. doi:10.1096/fj.09-143388. PMID   20065108. S2CID   23976702.