Evocative/suppression testing | |
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OPS-301 code | 1-797 |
Evocative/suppression testing refers to a class of tests performed where one substance is measured both before and after the administration of another substance to determine if the levels are stimulated ("evocative") or suppressed. [1]
They are most commonly performed in the evaluation of possible endocrine disorders.[ citation needed ]
Certain tests are performed in the evaluation of multiple conditions, and not all listed substances may be measured in each test.
Examples include:
Test name | Substance administered | Substance measured | Condition evaluated |
---|---|---|---|
combined rapid anterior pituitary evaluation panel | insulin, GnRH, TRH | ACTH and cortisol, FSH, HGH, LH, prolactin, TSH | hypopituitarism |
TRH stimulation test | TRH | TSH | secondary hypothyroidism |
ACTH stimulation test | ACTH | cortisol, 17α-hydroxyprogesterone | adrenal insufficiency, Congenital adrenal hyperplasia (21-hydroxylase, 3 beta) |
metyrapone panel | metyrapone | cortisol, 11-deoxycortisol | adrenal insufficiency |
dexamethasone suppression test | dexamethasone | cortisol | Cushing's syndrome |
captopril suppression test | captopril | aldosterone | primary aldosteronism |
captopril challenge test | captopril | renin | renal artery stenosis |
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