Ferric derisomaltose

Last updated

Ferric derisomaltose
Clinical data
Trade names Monoferric, Monofer
Other namesFDI
AHFS/Drugs.com Monograph
License data
Routes of
administration 		Intravenous
ATC code
  • None
Legal status
Legal status
Identifiers
  • iron(3+);(2S,3R,4R,5R)-6-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]oxan-2-yl]oxyhexane-1,2,3,4,5-pentol
CAS Number
PubChem CID
DrugBank
UNII
KEGG
Chemical and physical data
Formula C18H34FeO16+3
Molar mass 562.299 g·mol−1
3D model (JSmol)
  • C(C1C(C(C(C(O1)OCC2C(C(C(C(O2)OCC(C(C(C(CO)O)O)O)O)O)O)O)O)O)O)O.[Fe+3]
  • InChI=1S/C18H34O16.Fe/c19-1-5(21)9(23)10(24)6(22)3-31-17-16(30)14(28)12(26)8(34-17)4-32-18-15(29)13(27)11(25)7(2-20)33-18;/h5-30H,1-4H2;/q;+3/t5-,6+,7+,8+,9+,10+,11+,12+,13-,14-,15+,16+,17-,18-;/m0./s1
  • Key:JTQTXQSGPZRXJF-DOJSGGEQSA-N

Ferric derisomaltose, sold under the brand name Monoferric among others, is a medication for the treatment of iron deficiency anemia in adults who have intolerance to oral iron or have had unsatisfactory response to oral iron or who have non-hemodialysis dependent chronic kidney disease (NDD-CKD). [4] It was approved for use in the United States in January 2020. [4] [5] [6] It is given intravenously. [4]

References

  1. ↑ "Monofer iron (as ferric derisomaltose) 1000 mg/10 mL solution for injection vial (290834)". Therapeutic Goods Administration (TGA). 26 May 2022. Archived from the original on 14 April 2023. Retrieved 9 April 2023.
  2. ↑ "Prescription medicines and biologicals: TGA annual summary 2017". Therapeutic Goods Administration (TGA). 21 June 2022. Archived from the original on 31 March 2024. Retrieved 31 March 2024.
  3. ↑ "Regulatory Decision Summary for Monoferric". 23 October 2014. Archived from the original on 7 June 2022. Retrieved 7 June 2022.
  4. 1 2 3 4 "Monoferric- ferric derisomaltose solution". DailyMed. 24 January 2020. Archived from the original on 1 October 2020. Retrieved 16 February 2020.
  5. ↑ "Monoferric approval letter" (PDF). U.S. Food and Drug Administration (FDA). 16 January 2020. Archived from the original (PDF) on 17 February 2020. Retrieved 16 February 2020.PD-icon.svg This article incorporates text from this source, which is in the public domain .
  6. ↑ "Drug Approval Package: Monoferric Injection". U.S. Food and Drug Administration (FDA). 7 May 2020. Archived from the original on 1 October 2020. Retrieved 13 August 2020.


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