Formaldehyde transketolase

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formaldehyde transketolase
Identifiers
EC no. 2.2.1.3
CAS no. 76774-46-4
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / QuickGO
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PMC articles
PubMed articles
NCBI proteins

In enzymology, a formaldehyde transketolase (EC 2.2.1.3) is an enzyme that catalyzes the chemical reaction

D-xylulose 5-phosphate + formaldehyde glyceraldehyde 3-phosphate + glycerone

Thus, the two substrates of this enzyme are D-xylulose 5-phosphate and formaldehyde, whereas its two products are glyceraldehyde 3-phosphate and glycerone.

This enzyme belongs to the family of transferases, specifically those transferring aldehyde or ketonic groups (transaldolases and transketolases, respectively). The systematic name of this enzyme class is D-xylulose-5-phosphate:formaldehyde glycolaldehydetransferase. This enzyme is also called dihydroxyacetone synthase. This enzyme participates in methane metabolism. It employs one cofactor, thiamin diphosphate.

References