Glycine transaminase

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glycine transaminase
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EC no. 2.6.1.4
CAS no. 9032-99-9
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In enzymology, a glycine transaminase (EC 2.6.1.4) is an enzyme that catalyzes the chemical reaction

glycine + 2-oxoglutarate glyoxylate + L-glutamate

Thus, the two substrates of this enzyme are glycine and 2-oxoglutarate, whereas its two products are glyoxylate and L-glutamate.

This reactions strongly favours synthesis of glycine. [1] This enzyme belongs to the family of transferases, specifically the transaminases, which transfer nitrogenous groups. The systematic name of this enzyme class is glycine:2-oxoglutarate aminotransferase. Other names in common use include glutamic-glyoxylic transaminase, glycine aminotransferase, glyoxylate-glutamic transaminase, L-glutamate:glyoxylate aminotransferase, and glyoxylate-glutamate aminotransferase. This enzyme participates in glycine, serine and threonine metabolism. It employs one cofactor, pyridoxal phosphate.

Related Research Articles

<span class="mw-page-title-main">Aspartate transaminase</span> Enzyme involved in amino acid metabolism

Aspartate transaminase (AST) or aspartate aminotransferase, also known as AspAT/ASAT/AAT or (serum) glutamic oxaloacetic transaminase, is a pyridoxal phosphate (PLP)-dependent transaminase enzyme that was first described by Arthur Karmen and colleagues in 1954. AST catalyzes the reversible transfer of an α-amino group between aspartate and glutamate and, as such, is an important enzyme in amino acid metabolism. AST is found in the liver, heart, skeletal muscle, kidneys, brain, red blood cells and gall bladder. Serum AST level, serum ALT level, and their ratio are commonly measured clinically as biomarkers for liver health. The tests are part of blood panels.

In enzymology, a 2-aminoadipate transaminase is an enzyme that catalyzes the chemical reaction

<span class="mw-page-title-main">4-aminobutyrate transaminase</span> Class of enzymes

In enzymology, 4-aminobutyrate transaminase, also called GABA transaminase or 4-aminobutyrate aminotransferase, or GABA-T, is an enzyme that catalyzes the chemical reaction:

In enzymology, a 4-hydroxyglutamate transaminase is an enzyme that catalyzes the chemical reaction

In enzymology, a 5-aminovalerate transaminase is an enzyme that catalyzes the chemical reaction

<span class="mw-page-title-main">Alanine—glyoxylate transaminase</span>

In enzymology, an alanine-glyoxylate transaminase is an enzyme that catalyzes the chemical reaction

In enzymology, an aromatic-amino-acid-glyoxylate transaminase is an enzyme that catalyzes the chemical reaction

In enzymology, a cysteine-conjugate transaminase is an enzyme that catalyzes the chemical reaction

In enzymology, a cysteine transaminase is an enzyme that catalyzes the chemical reaction

In enzymology, a diaminobutyrate-2-oxoglutarate transaminase is an enzyme that catalyzes the chemical reaction

In enzymology, a dihydroxyphenylalanine transaminase is an enzyme that catalyzes the chemical reaction

In enzymology, a dTDP-4-amino-4,6-dideoxy-D-glucose transaminase is an enzyme that catalyzes the chemical reaction

In enzymology, a glycine-oxaloacetate transaminase is an enzyme that catalyzes the chemical reaction

<span class="mw-page-title-main">Histidinol-phosphate transaminase</span>

In enzymology, a histidinol-phosphate transaminase is an enzyme that catalyzes the chemical reaction

In enzymology, a kynurenine-glyoxylate transaminase is an enzyme that catalyzes the chemical reaction:

In enzymology, a leucine transaminase is an enzyme that catalyzes the chemical reaction

In enzymology, a (S)-3-amino-2-methylpropionate transaminase is an enzyme that catalyzes the chemical reaction

In enzymology, a succinyldiaminopimelate transaminase is an enzyme that catalyzes the chemical reaction

In enzymology, a taurine-2-oxoglutarate transaminase is an enzyme that catalyzes the chemical reaction.

Phosphoserine transaminase is an enzyme with systematic name O-phospho-L-serine:2-oxoglutarate aminotransferase. This enzyme catalyses the following chemical reaction

References

  1. ↑ Textbook of Biochemistry for Medical Students, by DM Vasudevan, Sreekumari S, Kannan Vaidyanathan, 9th edition, page 283.


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