Helicobacter bilis

Last updated

Helicobacter bilis
Helicobacter sp 01.jpg
Scanning electron micrograph of Helicobacter bilis bacteria
Scientific classification Red Pencil Icon.png
Domain: Bacteria
Phylum: Campylobacterota
Class: "Campylobacteria"
Order: Campylobacterales
Family: Helicobacteraceae
Genus: Helicobacter
Species:
H. bilis
Binomial name
Helicobacter bilis
Fox et al., 1995

Helicobacter bilis is a bacterium in the Helicobacteraceae family, Campylobacterales order. [1] It is a fusiform bacterium with three to 14 multiple bipolar sheathed flagella and periplasmic fibers wrapped around the cell. It is resistant to cephalothin and nalidixic acid, but sensitive to metronidazole. Like Helicobacter hepaticus , it colonizes the bile, liver, and intestine of mice, and is associated with multifocal chronic hepatitis and hepatocellular tumors. [2]

Contents

This strain was originally isolated from a 47-year-old man with a one-month history of diarrhea, fever, and lower abdominal pain, and designated Flexispira rappiniRomero et al. 1988. Hänninen et al. (2005) proposed to include this taxon in the species Helicobacter bilis, although based on 16S rRNA gene sequence, it is one of 10 distinct groups, which has been called Helicobacter sp. flexispira taxon 8 (provisionally Helicobacter rappini) [Dewhirst et al. 2000]. H. rappini has also been isolated from the feces of healthy people, dogs, and mice, as well as from patients with bacteremia. H. bilis and the other taxa include isolates from a wide range of host species, and have been associated with diarrhea, hepatitis, cholangitis, gallstones, liver cancer, and ovine abortion.

Related Research Articles

<i>Helicobacter</i> Genus of bacteria

Helicobacter is a genus of Gram-negative bacteria possessing a characteristic helical shape. They were initially considered to be members of the genus Campylobacter, but in 1989, Goodwin et al. published sufficient reasons to justify the new genus name Helicobacter. The genus Helicobacter contains about 35 species.

Hepatitis A Acute infectious disease of the liver

Hepatitis A is an infectious disease of the liver caused by Hepatovirus A (HAV); it is a type of viral hepatitis. Many cases have few or no symptoms, especially in the young. The time between infection and symptoms, in those who develop them, is 2–6 weeks. When symptoms occur, they typically last 8 weeks and may include nausea, vomiting, diarrhea, jaundice, fever, and abdominal pain. Around 10–15% of people experience a recurrence of symptoms during the 6 months after the initial infection. Acute liver failure may rarely occur, with this being more common in the elderly.

<i>Vibrio vulnificus</i> Species of pathogenic bacterium found in water

Vibrio vulnificus is a species of Gram-negative, motile, curved rod-shaped (bacillus), pathogenic bacteria of the genus Vibrio. Present in marine environments such as estuaries, brackish ponds, or coastal areas, V. vulnificus is related to V. cholerae, the causative agent of cholera. At least one strain of V. vulnificus is bioluminescent.

Chlamydia muridarum is an intracellular bacterial species that at one time belonged to Chlamydia trachomatis. However, C. trachomatis naturally only infects humans and C. muridarum naturally infects only members of the family Muridae.

<i>Murine coronavirus</i> Species of virus

Murine coronavirus (M-CoV) is a virus in the genus Betacoronavirus that infects mice. Belonging to the subgenus Embecovirus, murine coronavirus strains are enterotropic or polytropic. Enterotropic strains include mouse hepatitis virus (MHV) strains D, Y, RI, and DVIM, whereas polytropic strains, such as JHM and A59, primarily cause hepatitis, enteritis, and encephalitis. Murine coronavirus is an important pathogen in the laboratory mouse and the laboratory rat. It is the most studied coronavirus in animals other than humans, and has been used as an animal disease model for many virological and clinical studies.

Limosilactobacillus reuteri is a lactic acid bacterium found in a variety of natural environments, including the gastrointestinal tract of humans and other animals. It does not appear to be pathogenic and may have health effects.

Plasmodium yoelii is a parasite of the genus Plasmodium subgenus Vinckeia. As in all Plasmodium species, P. yoelii has both vertebrate and insect hosts. The vertebrate hosts for this parasite are mammals.

Helicobacter pullorum is a bacterium in the Helicobacteraceae family, Campylobacterales order. It was isolated from the liver, duodenum, and caecum of broiler and layer chickens, and from humans with gastroenteritis. It is a nongastric urease-negative Helicobacter species colonizing the lower bowel.

Helicobacter canis is a bacterium in the Helicobacteraceae family, Campylobacterales order. Its type strain is NCTC 12739T. It colonises the lower bowel, but is also present in cases of hepatitis. Besides infecting dogs, this bacterium is known to cause infections in immunocompromised humans.

Helicobacter hepaticus is a bacterium in the Helicobacteraceae family, Campylobacterales order.

Helicobacter rodentium is a bacterium in the Helicobacteraceae family, Campylobacterales order. It is a spiral-shaped bacterium with a bipolar, single, nonsheathed flagellum. It is resistant to cephalothin and nalidixic acid. Its type strain is MIT 95-1707. Its name refers to the species first being isolated from mice.

Helicobacter muridarum is a bacterium in the Helicobacteraceae family, Campylobacterales order. It is microaerophilic and helical and was first isolated from the intestinal mucosa of rodents, hence its name. It is characterised by the presence of 9 to 11 periplasmic fibers which appear as concentric helical ridges on the surface of each cell. The cells are motile and have bipolar tufts of 10 to 14 sheathed flagella. These bacteria are nutritionally fastidious and physiologically similar to other Helicobacter species and Wolinella succinogenes, but can be differentiated from these organisms by their unique cellular ultrastructure. ST1T is its type strain.

Helicobacter felis is a bacterial species in the Helicobacteraceae family, Campylobacterales order, Helicobacter genus. This bacterium is Gram-negative, microaerophilic, urease-positive, and spiral-shaped. Its type strain is CS1T. It can be pathogenic.

Helicobacter acinonychis is a bacterium in the Helicobacteraceae family, Campylobacterales order. It was first isolated from cheetahs with gastritis, so has been associated with this disease in this particular species and others of its kind. It is Gram-negative, spiral-shaped, and grows under microaerophilic conditions. The type strain is 90-119.

The altered Schaedler flora (ASF) is a community of eight bacterial species: two lactobacilli, one Bacteroides, one spiral bacterium of the Flexistipes genus, and four extremely oxygen sensitive (EOS) fusiform-shaped species. The bacteria are selected for their dominance and persistence in the normal microflora of mice, and for their ability to be isolated and grown in laboratory settings. Germ-free animals, mainly mice, are colonized with ASF for the purpose of studying the gastrointestinal (GI) tract. Intestinal mutualistic bacteria play an important role in affecting gene expression of the GI tract, immune responses, nutrient absorption, and pathogen resistance. The standardized microbial cocktail enabled the controlled study of microbe and host interactions, role of microbes, pathogen effects, and intestinal immunity and disease association, such as cancer, inflammatory bowel disease, diabetes, and other inflammatory or autoimmune diseases. Also, compared to germfree animals, ASF mice have fully developed immune system, resistance to opportunistic pathogens, and normal GI function and health, and are a great representation of normal mice.

Helicobacter trogontum is a bacterium in the Helicobacteraceae family, Campylobacterales order. It was first isolated from rat intestine. It is Gram-negative, its cells are rod-shaped with pointed ends, and its protoplasmic cylinder is entwined with periplasmic fibers. It is microaerophilic. The type strain is LRB 8581.

Helicobacter anseris is a bacterium in the Helicobacteraceae family, Campylobacterales order. It is Gram-negative, microaerophilic, spiral to curve-shaped, being first isolated from the faeces of geese.

Helicobacter brantae is a bacterium in the Helicobacteraceae family, Campylobacterales order. It is Gram-negative, microaerophilic, spiral to curve-shaped, being first isolated from the faeces of geese.

Helicobacter typhlonius is a Gram-negative bacterium and opportunistic pathogen found in the genus Helicobacter. Only 35 known species are in this genus, which was described in 1982. H. typhlonius has a small number of close relatives, including Helicobacter muridarum, Helicobacter trogontum, and Helicobacter hepaticus, with the latter being the closest relative and much more prevalent.

Helicobacter cetorum is a Gram-negative, microaerophilic, spiral (helical) bacterium that is usually found in the stomachs of whales and dolphins. Based on 16S rRNA sequencing, its genome is very similar to that of Helicobacter pylori in that it can cause gastric disease in these animals. Originally isolated among Atlantic white-sided dolphins and Beluga whales in 2000, H. cetorum has been associated with hemorrhages throughout its entire gastrointestinal tract, but its role has not yet been discovered. Prior to the discovery of H. cetorum, there have not been any other Helicobacter species reported in dolphins.

References

  1. Fox JG, Yan LL, Dewhirst FE, et al. (February 1995). "Helicobacter bilis sp. nov., a novel Helicobacter species isolated from bile, livers, and intestines of aged, inbred mice". Journal of Clinical Microbiology . 33 (2): 445–54. doi:10.1128/JCM.33.2.445-454.1995. PMC   227964 . PMID   7536217.
  2. Shomer NH, Dangler CA, Schrenzel MD, Fox JG (November 1997). "Helicobacter bilis-induced inflammatory bowel disease in scid mice with defined flora". Infection and Immunity . 65 (11): 4858–64. doi:10.1128/IAI.65.11.4858-4864.1997. PMC   175697 . PMID   9353076.

Further reading