Jedi2

Jedi2

Names
Preferred IUPAC name 2-methyl-5-thiophen-2-ylfuran-3-carboxylic acid
Identifiers
CAS Number	651005-90-2  Y
3D model (JSmol)	Interactive image
ChEBI	CHEBI:194934
ChEMBL	ChEMBL5181053
ChemSpider	2074902
PubChem CID	2796026
CompTox Dashboard (EPA)	DTXSID90383819
InChI InChI=1S/C10H8O3S/c1-6-7(10(11)12)5-8(13-6)9-3-2-4-14-9/h2-5H,1H3,(H,11,12) Key: YXDCRSXNEOKXDE-UHFFFAOYSA-N
SMILES CC1=C(C=C(O1)C2=CC=CS2)C(=O)O
Properties
Chemical formula	C10H8O3S
Molar mass	208.23 g·mol−1
Hazards
GHS labelling:
Pictograms
Signal word	Warning
Hazard statements	H302, H315, H317, H319
Precautionary statements	P261, P264, P264+P265, P270, P272, P280, P301+P317, P302+P352, P305+P351+P338, P321, P330, P332+P317, P333+P317, P337+P317, P362+P364, P501
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

Jedi2 is a chemical compound which acts as an agonist for the mechanosensitive ion channel PIEZO1, and is used in research into the function of touch perception. ^{[1] [2]}

See also

• Yoda1 and Jedi1

References

1. Wang Y, Chi S, Guo H, Li G, Wang L, Zhao Q, et al. (April 2018). "A lever-like transduction pathway for long-distance chemical- and mechano-gating of the mechanosensitive Piezo1 channel". Nature Communications. 9 (1): 1300. Bibcode:2018NatCo...9.1300W. doi: 10.1038/s41467-018-03570-9 . PMC   5880808 . PMID   29610524.
2. Fang XZ, Zhou T, Xu JQ, Wang YX, Sun MM, He YJ, Pan SW, Xiong W, Peng ZK, Gao XH, Shang Y (January 2021). "Structure, kinetic properties and biological function of mechanosensitive Piezo channels". Cell & Bioscience. 11 (1): 13. doi: 10.1186/s13578-020-00522-z . PMC   7796548 . PMID   33422128.