Katherine Bennett Ensor is an American statistician specializing in numerous methods in computational and statistical analysis of time series data, stochastic process modeling, and estimation to forecast issues in public health, community informatics, computational finance, and environmental statistics.
Ensor is the Noah G. Harding Professor of Statistics and Director of the Center for Computational Finance and Economic Systems at Rice University. From 2016–2022, she was Director of the Kinder Institute Urban Data Platform, a data resource initiative for the Greater Houston area that includes the Texas Flood and COVID-19 registries. She is an Executive Team Member for Houston Wastewater Epidemiology, a SARS-CoV-2 wastewater monitoring initiative between Rice University, the Houston Health Department, Houston Public Works, and the City of Houston. [1] In August 2022, Houston Wastewater Epidemiology was named a National Wastewater Surveillance System (NWSS) Center of Excellence by the U.S. Centers for Disease Control and Prevention. [2]
Ensor's statistical and computational methods for the development of modeling frameworks pinpoint, track and forecast issues across a wide variety of fields.
Since the start of her academic career, a focus of her research has sought a deeper understanding of problems in energy, [3] quantitative finance [4] [5] and risk management. [6] In 2002, she collaborated with university and industry partners to establish the Center for Computational Finance and Economic Systems (CoFES). She has since continued to serve as the center’s director and has developed numerous programs in graduate and undergraduate research and education. [7]
Ensor is widely known for her expertise in community analytics, which has grown through her career-long commitment to environmental and health-based research. Through collaborations with cross-disciplinary groups of educators, scientists, engineers, and city and public health professionals, she has quantitatively assessed air quality and human exposure to environmental contaminants. The work has also included the discovery of a correlation between ozone and heart attacks, and of geographic patterns in severe asthma attacks in schoolchildren. [8] [9] [10]
In May 2020, Ensor and collaborators at Rice University, the Houston Health Department, Houston Public Works, and the City of Houston, began conducting ongoing testing of the city’s wastewater treatment system for the presence of SARS-CoV-2, the virus that causes COVID-19. [11]
The wastewater monitoring system has also been adapted to provide public health information on seasonal influenza, the respiratory syncytial virus (RSV), mpox and other human pathogens. [12] [13]
As Director of the Kinder Institute Urban Data Platform from 2016–2022, Ensor investigated historical Houston flood event trends and Hurricane Harvey and on the health and housing impacts of the COVID-19 pandemic and COVID-19 vaccines. [14] Additional studies have investigated mitigating risk and the affects climate change. [15]
Ensor advises on statistics and data science as a member of the Board of Directors for the Accreditation Board for Engineering and Technology (ABET) – Computer Science Accreditation Board (CSAB). She serves on the Board of Scientific Counselors for the National Institute of Environmental Health Sciences (NIEHS) and the Board of Trustees for the National Science Foundation (NSF) Institute for Pure and Applied Mathematics (IPAM). She was the 117th President of the American Statistical Association’s (ASA) Board of Directors (2021–2022) [16] and Vice President of ASA’s Board of Directors from 2016–2018. She was a member of the National Academies of Sciences, Engineering and Medicine (NASEM) Committee on Applied and Theoretical Statistics (CATS) from 2015–2021. [17]
Ensor earned bachelor's and master's degrees in mathematics from Arkansas State University in 1981 and 1982. She completed her Ph.D. in statistics in 1986 from Texas A&M University; [17] her dissertation, supervised by H. Joseph Newton, was Some Results in Autoregressive Modeling. [18] She has been on the Rice faculty since 1987. [17]
In epidemiology, the basic reproduction number, or basic reproductive number, denoted , of an infection is the expected number of cases directly generated by one case in a population where all individuals are susceptible to infection. The definition assumes that no other individuals are infected or immunized. Some definitions, such as that of the Australian Department of Health, add the absence of "any deliberate intervention in disease transmission". The basic reproduction number is not necessarily the same as the effective reproduction number , which is the number of cases generated in the current state of a population, which does not have to be the uninfected state. is a dimensionless number and not a time rate, which would have units of time−1, or units of time like doubling time.
GISAID, the Global Initiative on Sharing All Influenza Data, previously the Global Initiative on Sharing Avian Influenza Data, is a global science initiative established in 2008 to provide access to genomic data of influenza viruses. The database was expanded to include the coronavirus responsible for the COVID-19 pandemic, as well as other pathogens. The database has been described as "the world's largest repository of COVID-19 sequences". GISAID facilitates genomic epidemiology and real-time surveillance to monitor the emergence of new COVID-19 viral strains across the planet.
Sunetra Gupta is an Indian-born British infectious disease epidemiologist and a professor of theoretical epidemiology at the Department of Zoology, University of Oxford. She has performed research on the transmission dynamics of various infectious diseases, including malaria, influenza and COVID-19, and has received the Scientific Medal of the Zoological Society of London and the Rosalind Franklin Award of the Royal Society. She is a member of the scientific advisory board of Collateral Global, an organisation which examines the global impact of COVID-19 restrictions.
Economic epidemiology is a field at the intersection of epidemiology and economics. Its premise is to incorporate incentives for healthy behavior and their attendant behavioral responses into an epidemiological context to better understand how diseases are transmitted. This framework should help improve policy responses to epidemic diseases by giving policymakers and health-care providers clear tools for thinking about how certain actions can influence the spread of disease transmission.
The Chinese Center for Disease Control and Prevention is an institution directly under the National Health Commission, based in Changping District, Beijing, China.
Soumya Swaminathan is an Indian paediatrician and clinical scientist known for her research on tuberculosis and HIV. From 2019 to 2022, she served as the chief scientist at the World Health Organization under the leadership of Director General Tedros Adhanom Ghebreyesus. Previously, from October 2017 to March 2019, she was the Deputy Director General of Programmes (DDP) at the World Health Organization.
Tanja Stadler is a mathematician and professor of computational evolution at the Swiss Federal Institute of Technology. She’s the current president of the Swiss Scientific Advisory Panel COVID-19 and Vize-Chair of the Department of Biosystems Science and Engineering at ETH Zürich.
Bhramar Mukherjee is an Indian-American biostatistician, data scientist, professor and researcher. She is currently serving as the inaugural Senior Associate Dean of Public Health Data Science and Data Equity at the Yale School of Public Health from August 1, 2024. She is also appointed as Anna MR Lauder Professor of Biostatistics, Professor of Epidemiology with secondary appointment as Professor of Statistics and Data Science at Yale University.
Coronavirus disease 2019 (COVID-19) is a contagious disease caused by the coronavirus SARS-CoV-2. The first known case was identified in Wuhan, China, in December 2019. Most scientists believe the SARS-CoV-2 virus entered into human populations through natural zoonosis, similar to the SARS-CoV-1 and MERS-CoV outbreaks, and consistent with other pandemics in human history. Social and environmental factors including climate change, natural ecosystem destruction and wildlife trade increased the likelihood of such zoonotic spillover. The disease quickly spread worldwide, resulting in the COVID-19 pandemic.
Caitlin M. Rivers is an American epidemiologist who as Senior Scholar at the Johns Hopkins Center for Health Security and assistant professor at the Johns Hopkins Bloomberg School of Public Health, specializing on improving epidemic preparedness. Rivers is currently working on the American response to the COVID-19 pandemic with a focus on the incorporation of infectious disease modeling and forecasting into public health decision making.
Allison Joan McGeer is a Canadian infectious disease specialist in the Sinai Health System, and a professor in the Department of Laboratory Medicine and Pathobiology at the University of Toronto. She also appointed at the Dalla Lana School of Public Health and a Senior Clinician Scientist at the Lunenfeld-Tanenbaum Research Institute, and is a partner of the National Collaborating Centre for Infectious Diseases. McGeer has led investigations into the severe acute respiratory syndrome outbreak in Toronto and worked alongside Donald Low. During the COVID-19 pandemic, McGeer has studied how SARS-CoV-2 survives in the air and has served on several provincial committees advising aspects of the Government of Ontario's pandemic response.
Catherine Jane Noakes is a British mechanical engineer who is Professor of Environmental Engineering for Buildings at the University of Leeds. Noakes specialises in airborne infections and the transport of airborne pathogens. During the COVID-19 pandemic, Noakes served on the Government of the United Kingdom Scientific Advisory Group for Emergencies (SAGE).
Germaine M. Buck Louis was the Dean of the George Mason University College of Health and Human Services and professor in Mason’s Department of Global and Community Health. She led the College in becoming Virginia's first accredited College of Public Health prior to her retirement in 2022. Her expertise focuses on environmental exposures and human health, particularly human reproduction and pregnancy. Prior to her appointment as dean at George Mason in 2017, she was the founding Director for the Division of Intramural Population Health Research at the Eunice Kennedy Shriver National Institute of Child Health and Human Development.
The transmission of COVID-19 is the passing of coronavirus disease 2019 from person to person. COVID-19 is mainly transmitted when people breathe in air contaminated by droplets/aerosols and small airborne particles containing the virus. Infected people exhale those particles as they breathe, talk, cough, sneeze, or sing. Transmission is more likely the closer people are. However, infection can occur over longer distances, particularly indoors.
Wastewater surveillance is the process of monitoring wastewater for contaminants. Amongst other uses, it can be used for biosurveillance, to detect the presence of pathogens in local populations, and to detect the presence of psychoactive drugs.
Wastewater-based epidemiology analyzes wastewater to determine the consumption of, or exposure to, chemicals or pathogens in a population. This is achieved by measuring chemical or biomarkers in wastewater generated by the people contributing to a sewage treatment plant catchment. Wastewater-based epidemiology has been used to estimate illicit drug use in communities or populations, but can be used to measure the consumption of alcohol, caffeine, various pharmaceuticals and other compounds. Wastewater-based epidemiology has also been adapted to measure the load of pathogens such as SARS-CoV-2 in a community. It differs from traditional drug testing, urine or stool testing in that results are population-level rather than individual level. Wastewater-based epidemiology is an interdisciplinary endeavour that draws on input from specialists such as wastewater treatment plant operators, analytical chemists and epidemiologists.
The COVID-19 pandemic has affected animals directly and indirectly. SARS-CoV-2, the virus that causes COVID-19, is zoonotic, which likely to have originated from animals such as bats and pangolins. Human impact on wildlife and animal habitats may be causing such spillover events to become much more likely. The largest incident to date was the 2020 Danish mink cull, the slaughter of all 17 million mink in Denmark after it was discovered that they were infected with a mutant strain of the virus.
Rochelle Paula Walensky is an American physician-scientist who served as the director of the U.S. Centers for Disease Control and Prevention from 2021 to 2023 and served as the administrator of the Agency for Toxic Substances and Disease Registry in her capacity as the director of the U.S. Centers for Disease Control and Prevention from 2021 to 2023. On May 5, 2023, she announced her resignation, effective June 30, 2023. Prior to her appointment at the CDC, she had served as the chief of the Division of Infectious Diseases at Massachusetts General Hospital and a professor of medicine at Harvard Medical School. Walensky is an expert on HIV/AIDS.
Vittoria Colizza is an Italian scientist, research director at INSERM and a specialist in mathematical modeling of infectious disease and computational epidemiology. In particular, she has carried out research on the modeling of seasonal and pandemic flu, Ebola and the COVID-19 pandemic.
Biobot Analytics is an American biotechnology company that specializes in wastewater-based epidemiology headquartered in Cambridge, Massachusetts. The company analyzes wastewater samples to measure the concentration of various substances, including pathogens, illicit drugs, and other public health indicators. Biobot was founded in 2017 at MIT by computational biologist Mariana Matus and architect Newsha Ghaeli.