Left-right determination factor 2 is a protein that in humans is encoded by the LEFTY2 gene. [5]
Left-right determination factor 2 is a protein that in humans is encoded by the LEFTY2 gene. [5]
This gene encodes a member of the TGF-beta family of proteins. The encoded protein is secreted and plays a role in left-right asymmetry determination of organ systems during development. The protein may also play a role in endometrial bleeding. Mutations in this gene have been associated with left-right axis malformations, particularly in the heart and lungs. Some types of infertility have been associated with dysregulated expression of this gene in the endometrium. Alternative processing of this protein can yield three different products. This gene is closely linked to both a related family member and a related pseudogene. Alternate splicing of this gene results in multiple transcript variants.
Zinc finger FYVE domain-containing protein 9 or SARA is a protein that in humans is encoded by the ZFYVE9 gene. SARA contains a double zinc finger.
BMP and activin membrane-bound inhibitor homolog , also known as BAMBI, is a protein which in humans is encoded by the BAMBI gene.
Transforming growth factor, beta receptor II (70/80kDa) is a TGF beta receptor. TGFBR2 is its human gene.
LEM domain-containing protein 3 (LEMD3), also known as MAN1, is an integral protein in the inner nuclear membrane (INM) of the nuclear envelope. It is encoded by the LEMD3 gene and was first identified after it was isolated from the serum of a patient with a collagen vascular disease.
Growth differentiation factor 10 (GDF10) also known as bone morphogenetic protein 3B (BMP-3B) is a protein that in humans is encoded by the GDF10 gene.
Bone morphogenetic protein receptor type-1B also known as CDw293 is a protein that in humans is encoded by the BMPR1B gene.
Epigen also known as epithelial mitogen is a protein that in humans is encoded by the EPGN gene.
MYC proto-oncogene, bHLH transcription factor is a protein that in humans is encoded by the MYC gene which is a member of the myc family of transcription factors.
Platelet-derived growth factor subunit B is a protein that in humans is encoded by the PDGFB gene.
Latent-transforming growth factor beta-binding protein 1 is a protein that in humans is encoded by the LTBP1 gene.
TSC22 domain family protein 1 is a protein that in humans is encoded by the TSC22D1 gene.
Latent-transforming growth factor beta-binding protein 3 is a protein that in humans is encoded by the LTBP3 gene.
Latent-transforming growth factor beta-binding protein 2 is a protein that in humans is encoded by the LTBP2 gene.
LIM homeobox transcription factor 1, alpha, also known as LMX1A, is a protein which in humans is encoded by the LMX1A gene.
Inhibin beta C chain is a protein that in humans is encoded by the INHBC gene.
Neuronal protein 3.1 is a protein that in humans is encoded by the NREP gene. It is highly expressed in the brain.
Kruppel-like factor 7 (ubiquitous), also known as KLF7, is a protein which in humans is encoded by the KLF7 gene.
Insulin like 6 is a protein that in humans is encoded by the INSL6 gene.
Left-right determination factor 1 is a protein that in humans is encoded by the LEFTY1 gene.
TM2 domain containing 1 is a protein that in humans is encoded by the TM2D1 gene.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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