Cerebrospinal fluid (CSF) is a clear, colorless body fluid found within the tissue that surrounds the brain and spinal cord of all vertebrates.
The medulla oblongata or simply medulla is a long stem-like structure which makes up the lower part of the brainstem. It is anterior and partially inferior to the cerebellum. It is a cone-shaped neuronal mass responsible for autonomic (involuntary) functions, ranging from vomiting to sneezing. The medulla contains the cardiovascular center, the respiratory center, vomiting and vasomotor centers, responsible for the autonomic functions of breathing, heart rate and blood pressure as well as the sleep–wake cycle. "Medulla" is from Latin, ‘pith or marrow’. And "oblongata" is from Latin, ‘lengthened or longish or elongated'.
The abducens nerve or abducent nerve, also known as the sixth cranial nerve, cranial nerve VI, or simply CN VI, is a cranial nerve in humans and various other animals that controls the movement of the lateral rectus muscle, one of the extraocular muscles responsible for outward gaze. It is a somatic efferent nerve.
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The brainstem is the posterior stalk-like part of the brain that connects the cerebrum with the spinal cord. In the human brain the brainstem is composed of the midbrain, the pons, and the medulla oblongata. The midbrain is continuous with the thalamus of the diencephalon through the tentorial notch, and sometimes the diencephalon is included in the brainstem.
In neuroanatomy, the ventricular system is a set of four interconnected cavities known as cerebral ventricles in the brain. Within each ventricle is a region of choroid plexus which produces the circulating cerebrospinal fluid (CSF). The ventricular system is continuous with the central canal of the spinal cord from the fourth ventricle, allowing for the flow of CSF to circulate.
The fourth ventricle is one of the four connected fluid-filled cavities within the human brain. These cavities, known collectively as the ventricular system, consist of the left and right lateral ventricles, the third ventricle, and the fourth ventricle. The fourth ventricle extends from the cerebral aqueduct to the obex, and is filled with cerebrospinal fluid (CSF).
The median aperture is an opening at the caudal portion of the roof of the fourth ventricle. It allows the flow of cerebrospinal fluid (CSF) from the fourth ventricle into the cisterna magna. The other openings of the fourth ventricle are the lateral apertures - one on either side. The median aperture varies in size but accounts for most of the outflow of CSF from the fourth ventricle.
There are four paired deep cerebellar nuclei embedded in the white matter centre of the cerebellum. The nuclei are the fastigial, globose, emboliform, and dentate nuclei.
The fastigial nucleus is located in each cerebellar hemisphere. It is one of the four paired deep cerebellar nuclei of the cerebellum.
The cisterna magna is the largest of the subarachnoid cisterns. It occupies the space created by the angle between the caudal/inferior surface of the cerebellum, and the dorsal/posterior surface of the medulla oblongata. The fourth ventricle communicates with the cistern via the unpaired midline median aperture. It is continuous inferiorly with the subarachnoid space of the spinal canal.
The cerebellopontine angle (CPA) is located between the cerebellum and the pons. The cerebellopontine angle is the site of the cerebellopontine angle cistern.
The vestibular nuclei (VN) are the cranial nuclei for the vestibular nerve located in the brainstem.
The lateral aperture, lateral aperture of fourth ventricle or foramen of Luschka is an opening at the lateral extremity of either lateral recess of the fourth ventricle opening anteriorly into the pontine cistern/lateral cerebellomedullary cistern at cerebellopontine angle. A tuft of choroid plexus commonly extends into the lateral aperture, partially obstructing CSF flow through this aperture.
The dorsal column nuclei are a pair of nuclei in the dorsal columns of the dorsal column–medial lemniscus pathway (DCML) in the brainstem. The name refers collectively to the cuneate nucleus and gracile nucleus, which are situated at the lower end of the medulla oblongata. Both nuclei contain second-order neurons of the DCML, which convey fine touch and proprioceptive information from the body to the brain via the thalamus.
The medullary striae of fourth ventricle are a landmark of the rhomboid fossa - the floor of the fourth ventricle. They are part of the auditory system. The medullary striae are formed by crossed-over anterior internal arcuate fibers - efferents of the arcuate nucleus of medulla oblongata - as they pass laterally beneath the ependyma of the fourth ventricle to reach the contralateral cerebellum. The striae pass over the dorsal aspect of the medial vestibular nucleus.
The tela choroidea is a region of meningeal pia mater that adheres to the underlying ependyma, and gives rise to the choroid plexus in each of the brain’s four ventricles. Tela is Latin for woven and is used to describe a web-like membrane or layer. The tela choroidea is a very thin part of the loose connective tissue of pia mater overlying and closely adhering to the ependyma. It has a rich blood supply. The ependyma and vascular pia mater – the tela choroidea, form regions of minute projections known as a choroid plexus that projects into each ventricle. The choroid plexus produces most of the cerebrospinal fluid of the central nervous system that circulates through the ventricles of the brain, the central canal of the spinal cord, and the subarachnoid space. The tela choroidea in the ventricles forms from different parts of the roof plate in the development of the embryo.
Serotonergic cell groups refer to collections of neurons in the central nervous system that have been demonstrated by histochemical fluorescence to contain the neurotransmitter serotonin (5-hydroxytryptamine). Since they are for the most part localized to classical brainstem nuclei, particularly the raphe nuclei, they are more often referred to by the names of those nuclei than by the B1-9 nomenclature. These cells appear to be common across most mammals and have two main regions in which they develop; one forms in the mesencephlon and the rostral pons and the other in the medulla oblongata and the caudal pons.
Perihypoglossal nuclei are three prominent groups of neurons in the caudal medulla oblongata near the hypoglossal nucleus: the nucleus prepositus hypoglossi, intercalated nucleus, and sublingual nucleus. They are involved in controlling eye movements: they send their principal projections to the three cranial nerve nuclei controlling extrinsic eye muscles via the medial longitudinal fasciculus.
