The Wyoming Cowboys have had 85 players drafted to the NFL since the first draft in 1936. Of those 84 players, 5 have been selected to a Pro Bowl, and 7 have been a part of a Super Bowl or NFL Championship winning team. Currently, 5 of those draftees still play in the NFL.
The highest drafted Cowboy is Josh Allen, taken 7th overall in 2018 Draft. The most Cowboys ever taken in a draft is 5, in 1968.
| B | Back | K | Kicker | NT | Nose tackle |
| C | Center | LB | Linebacker | FB | Fullback |
| DB | Defensive back | P | Punter | HB | Halfback |
| DE | Defensive end | QB | Quarterback | WR | Wide receiver |
| DT | Defensive tackle | RB | Running back | G | Guard |
| E | End | T | Offensive tackle | TE | Tight end |
| * | Selected to a Pro Bowl | ||||
| † | Won a Super Bowl championship/NFL Championship Game | ||||
| ‡ | Selected to a Pro Bowl and won a Super Bowl/NFL Championship Game | ||||
Note: No drafts held before 1920
| Year | Player | Debut Team | Position | Notes |
|---|---|---|---|---|
| 1972 | Nelson Munsey | CB | Baltimore Colts | — |
| 1979 | John Arnold | WR | Detroit Lions | — |
| 1980 | Mike Dennis | CB | New York Giants | — |
| Pat Ogrin | DT | Washington Redskins | — | |
| 1985 | Rick Donnelly | P | New England Patriots | — |
| 1988 | Craig Burnett | QB | Dallas Cowboys | — |
| 1996 | Joe Cummings | LB | Philadelphia Eagles | — |
| 1998 | Rob Bohlinger | T | Carolina Panthers | — |
| 2000 | Trent Gamble | S | Miami Dolphins | — |
| 2001 | Aaron Elling | K | Miami Dolphins | — |
| 2003 | Scottie Vines | WR | Green Bay Packers | — |
| Adam Goldberg | T | Minnesota Vikings | — | |
| 2004 | Malcom Floyd | WR | San Diego Chargers | — |
| 2010 | Mitch Unrein | DT | Houston Texans | — |
| 2012 | Tashaun Gipson | S | Cleveland Browns | — |
| 2013 | Kurt Taufa'asau | DT | Oakland Raiders | — |
| Mike Purcell | DT | San Francisco 49ers | — | |
| 2017 | Jacob Hollister | TE | New England Patriots | — |
| 2019 | Carl Granderson | DE | New Orleans Saints | — |
| Andrew Wingard | S | Jacksonville Jaguars | — | |
| 2020 | Tyler Hall | CB | Atlanta Falcons | — |
| 2024 | Frank Crum | OL | Denver Broncos | — |
| Easton Gibbs | LB | Seattle Seahawks | — | |
| Andrew Peasley | QB | New York Jets | — | |
| Treyton Welch | TE | Cleveland Browns | — |