List of largest selling pharmaceutical products

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Best selling pharmaceuticals of U.S. market

The top most selling pharmaceutical medicines (therapeutic and alternative) which are approved by the FDA used to treat different severe and chronic diseases. Pharmacies are selling and billing with the cooperation of different insurance companies affiliated with the private and federal links. The most essential pointers we need to check after approved standards by FDA which is mention in every medicine's packaging called med guide. Some most selling products needed to registered by the REMS program, there are different branches of REMS program according to intensity of patient's health conditions which addressed by the physician. first crucial point need to check is recall medication like class 1 which include adulteration and misbranding. some medicines are control substances in it which we consider in most selling products. IMPORTANT POINTS: drug name (generic and brand) drug class Main indication (side effects, drug interactions, benefits and effectiveness) manufacturer name !2015 !2016 !2017 !2018 !2019 |- |1 |adalimumab |rheumatoid arthritis |Humira |10.1 |13.5 |16.3 |18.4 |21.4 |- |2 |apixaban |anticoagulant |Eliquis |1.6 |3.0 |4.6 |7.1 |9.9 |- |3 |etanercept |rheumatoid arthritis |Enbrel |7.2 |7.6 |7.9 |8.0 |8.1 |- |4 |ustekinumab |psoriasis |Stelara |2.0 |2.6 |3.7 |5.0 |6.6 |- |5 |pembrolizumab |oncology |Keytruda |0.4 |0.7 |2.2 |4.3 |6.5 |}

Contents

Best selling pharmaceuticals of 2017/18

The top 16 best selling pharmaceuticals of 2017/18. [1]

RankDrugMain indicationTrade name2018 sales (million USD)2017 sales (million USD)
1 adalimumab rheumatoid arthritis Humira19 93618427
3 apixaban anticoagulant Eliquis98727395
4 lenalidomide multiple myeloma Revlimid96858187
5 nivolumab oncology Opdivo75705763
6 pembrolizumab oncology Keytruda71713809
7 etanercept rheumatoid arthritis Enbrel71267885
8 trastuzumab breast cancer Herceptin69817013
9 bevacizumab colon cancer Avastin68476686
10 rituximab non-Hodgkin's lymphoma Rituxan,

MabThera

67507298
11 rivaroxaban anticoagulant Xarelto65896234
12 aflibercept Eylea65515830
13 infliximab Remicade59087152
14 Pneumococcal conjugate vaccine Prevnar 13

Prevenar 13

58025601
15 ustekinumab Stelara51564011
16 pregabalin epilepsy Lyrica49705065

Largest selling pharmaceutical products of 2015

Drugs with sales above $5 billion in 2015 included: [2] [3]

RankDrugTrade nameTypeMain indicationsCompanySales (USD millions/year)∆ vs 2014
1 Adalimumab HumiraBiologic Rheumatoid arthritis AbbVie Inc. 14,0121,469
2 Ledipasvir/sofosbuvir HarvoniSmall molecule Hepatitis C Gilead Sciences 13,86411,737
3 Etanercept EnbrelBiologic Rheumatoid arthritis Amgen

Pfizer

8,6974,009
4 Infliximab RemicadeBiologic Crohn's Disease
Rheumatoid Arthritis 		Johnson & Johnson 8,3551,487
5 Rituximab Mabthera

Rituxan

Biologic Lymphoma

Leukemia

Autoimmune disorders

Roche

Genentech

7,1151,456
6 Insulin glargine LantusBiologic Diabetes mellitus Sanofi 7,02951
7 Bevacizumab AvastinBiologic Metastatic cancers Roche

Genentech

6,751270
8 Trastuzumab HerceptinBiologic Breast cancer Roche

Genentech

6,603265
9 Lenalidomide RevlimidSmall molecule Multiple myeloma

Myelodysplastic syndromes

Celgene 5,801821
10 Sofosbuvir SovaldiSmall molecule Hepatitis C Gilead Sciences 5,276(5,007)
11 Fluticasone propionate/salmeterol Seretide

Advair

Small molecule Asthma

Chronic obstructive pulmonary disease

GlaxoSmithKline 5,227(778)
12 Rosuvastatin CrestorSmall molecule Cardiovascular diseases AstraZeneca 5,017(495)

Best selling pharmaceuticals of 2013

For the fourth quarter of 2013, the largest selling drugs were: [4]

RankBrand Name(s)Generic NameSales Q1 2014 Sales ($000)Change from Q4 2013Company(ies)Disease/Medical UseFirst Approval DatePatent Expiration Date [5] [6]
1Abilify Aripiprazole 1,602,3292.23% Generic Psychosis, mania, and depressionNov-20022014-Oct
2Humira Adalimumab 1,561,8613.86% AbbVie Crohn's disease; Rheumatoid arthritisDec-20022016-Dec
3Nexium Esomeprazole 1,536,4350.74% Generic Gastrointestinal disordersMar-20002014-May
4Crestor Rosuvastatin 1,333,5024.53% AstraZeneca, Shionogi CholesterolNov-20022016-Jul
5Enbrel Etanercept 1,189,8441.46% Amgen Rheumatoid arthritisNov-19982012-Oct
6Advair Diskus, Seretide Fluticasone/salmeterol 1,147,3302.65% GlaxoSmithKline AsthmaAug-20002012-Mar
8Remicade Infliximab 994,020-2.71% Centocor Ortho Biotech, Inc., Mitsubishi Tanabe Pharma Crohn's disease; rheumatoid arthritisAug-1998n/a
9Lantus Solostar Insulin glargine 939,6919.39% Sanofi-Aventis Diabetes mellitus type 1 and 2Apr-20002011-Dec
10Neulasta Pegfilgrastim 854,508-4.90% Amgen NeutropeniaJan-2002Mon-20XX
11Copaxone Glatiramer 851,351-4.69% Generic Multiple sclerosisDec-1996Nov-2014
12Rituxan, MabThera Rituximab 746,766-0.16% Biogen Idec, Chugai Pharmaceutical, Genentech/Roche Non-Hodgkin’s lymphoma; rheumatoid arthritisNov-1997Mon-20XX
13Spiriva Tiotropium bromide 726,0573.39% Boehringer Ingelheim Chronic obstructive pulmonary diseaseApr-20022018-Jul
14Januvia Sitagliptin 700,9413.63% Merck & Co., Inc. Diabetes mellitus type 2Dec-19962017-Nov
15Lantus Insulin glargine 685,4615.84% Sanofi-Aventis Diabetes mellitus type 1 and 2Apr-2000Dec-2011
16Atripla Emtricitabine/tenofovir/efavirenz 679,4180.36% Gilead Sciences, Inc. HIV infectionDec-1996Mar-2015
17Cymbalta Duloxetine 664,186-23.06% Generic Depression; anxiety disordersAug-2004Dec-2013
18Avastin Bevacizumab 650,208-1.25% Genentech/Roche CancerFeb-2004Mon-20XX
19Lyrica Pregabalin 624,7742.82% Pfizer Neuropathic painJul-2004Jul-2019
20OxyContin Oxycodone 585,482-2.91% Generic PainDec-1996Mon-20XX
21Celebrex Celecoxib 580,3325.23% Generic Osteoarthritis; rheumatoid arthritisDec-1998May-2014
22Epogen Epoetin alfa 503,493-2.08% Amgen AnemiaJun-1989Mon-20XX
23Truvada Tenofovir/emtricitabine 542,8460.03% Gilead Sciences HIV infectionAug-2004Mon-20XX
24Diovan Valsartan 533,924-2.80% Generic HypertensionDec-1996Sep-2012
25Levemir Insulin detemir 424,1869.34% Novo Nordisk Diabetes mellitus type 1 and 2Dec-1990Mon-20XX
26Gleevec, Glivec Imatinib 498,1497.22% Novartis LeukemiaMay-2001Jan-2015
27Herceptin Trastuzumab 473,6321.53% Chugai Pharmaceutical, Genentech/Roche Breast cancerSep-1998Mon-20XX
28Vyvanse Lisdexamfetamine 447,1889.39% Shire Attention deficit hyperactivity disorderApr-2008Mon-20XX
29Lucentis Ranibizumab 460,621-0.84% Genentech Macular degenerationDec-1990Mon-20XX
30Zetia Ezetimibe 444,7314.04% Merck & Co., Schering-Plough CholesterolOct-20022017-Oct
31Combivent Ipratropium bromide/salbutamol 391,40420.28% Boehringer Ingelheim Chronic obstructive pulmonary diseaseOct-1996Mon-20XX
32Symbicort Budesonide/formoterol 407,6469.63% AstraZeneca AsthmaAug-2000Mon-20XX
33Namenda Memantine 434,766-6.00% Generic Alzheimer's diseaseOct-2003Apr-2014 [8]
34NovoLog FlexPen Insulin aspart 364,8707.84% Novo Nordisk Diabetes mellitus type 1 and 2Oct-1996Mon-20XX
35Xarelto Rivaroxaban 321,46218.72% Bayer Oral anticoagulantDec-1996Sep-2012
36NovoLog Insulin aspart 344,2353.86% Novo Nordisk Diabetes mellitus type 1 and 2Oct-1996Mon-20XX
37Humalog Insulin lispro 304,8666.15% Eli Lilly and Company Diabetes mellitus type 1 and 2Apr-1996Mon-20XX
38Suboxone Buprenorphine 321,892-2.11% Reckitt Benckiser Pharmaceuticals Inc. Pain; opioid addictionAug-2000Mon-20XX
40Viagra Sildenafil 300,4633.26% Pfizer Erectile dysfunctionMar-1998Mar-2012
41Seroquel XR Quetiapine 291,4942.22% Generic Psychosis; depressionSep-1997Mar-2012
33Incivo Telaprevir 370,8990.00% Johnson & Johnson Hepatitis C[ citation needed ]Dec-1990Mon-20XX
35AndroGel Testosterone gel351,7375.47% Generic Low testosterone levelsOct-2002Oct-2016
37Enoxaparin Enoxaparin 341,1846.55% Generic Deep-vein thrombosisMar-19932012-Aug
38Ritalin Methylphenidate 327,3462.26% Generic Attention deficit hyperactivity disorderAug-2000Mon-20XX
41ProAir HFA Salbutamol 306,46110.87% Teva Pharmaceuticals Asthma; chronic obstructive pulmonary diseaseOct-1996Mon-20XX
43Alimta Pemetrexed 302,7286.00% Eli Lilly and Company CancerFeb-2004Mon-20XX
44Victoza Liraglutide 301,4149.59% Novo Nordisk Diabetes mellitus type 2May-1909Mon-20XX
47Synagis Palivizumab 289,7040.00% MedImmune RSV infectionFeb-1998Aug-2012
48Avonex Interferon beta 1a 281,554-1.43% Biogen Idec Multiple sclerosisMay-1996Mon-20XX
49Renvela Sevelamer 280,91721.44% Generic HyperphosphatemiaApr-2002Apr-2016 [9]
50Rebif Interferon beta 1a 280,548-6.27% Serono Multiple sclerosisFeb-1998Mon-20XX
51Cialis Tadalafil 280,5184.58% Eli Lilly and Company, Lilly Icos Erectile dysfunctionNov-20022017-Nov
52Gilenya fingolimod 272,7014.05% Novartis Corporation Multiple sclerosisFeb-20002007-Jan
53Nasonex Mometasone 272,3455.67% Schering-Plough Allergic rhinitisOct-19972018-Oct
54Stelara Ustekinumab 270,59812.47% Johnson & Johnson Psoriasis; psoriatic arthritisApr-2000Mon-20XX
55Restasis Ciclosporin ophthalmic emulsion268,4636.30% Allergan, Inc, Lilly Icos Dry eye syndrome Nov-2002Mon-20XX
56Budesonide Budesonide 268,20126.81% Generic AsthmaAug-2000Mon-20XX
57Acetaminophen/hydrocodone Acetaminophen/hydrocodone 264,8146.67% Generic PainAug-2000Mon-20XX
58Flovent HFA Fluticasone propionate 263,07213.97% GlaxoSmithKline AsthmaMar-1996Mon-20XX
59 Lovaza Omega-3 fatty acid ethyl esters258,1772.90% GlaxoSmithKline CholesterolJun-2001Mon-20XX
60Prezista Darunavir 251,3723.54% Johnson & Johnson HIV infectionJun-2006Mon-20XX
61Isentress Raltegravir 248,9240.72% Merck & Co., Inc. HIV InfectionDec-1998Mon-20XX
62Janumet Sitagliptin/metformin 247,1504.65% Merck & Co., Inc. Diabetes mellitus type 2Dec-1998Mon-20XX
63Procrit, Eprex Epoetin alfa 241,535-10.09% Johnson & Johnson AnemiaDec-1990Mon-20XX
64Doxycycline Doxycycline 241,381-5.65% Generic Bacterial infectionsDec-1996Nov-2011
65Orencia Abatacept 241,1491.65% Bristol-Myers Squibb Company Rheumatoid arthritisAug-2000Mon-20XX
66Amphetamine/dextroamphetamine Amphetamine mixed salts 240,4822.78% Generic Attention deficit hyperactivity disorder; narcolepsyFeb-2004Mon-20XX
67Vesicare Solifenacin 240,4355.37% Astellas Pharma US Overactive bladderFeb-20002018-Nov
68Dexilant Dexlansoprazole 238,8977.57% Takeda Pharmaceuticals North America, Inc Gastrointestinal disordersDec-2004Jul-2012
69Humalog KwikPen Insulin lispro 238,41811.02% Eli Lilly and Company Diabetes mellitus type 1 and 2Apr-1996Mon-20XX
70Neupogen Filgrastim 229,912-2.70% Amgen NeutropeniaFeb-1991Mon-20XX
71Lidocaine Lidocaine 225,9030.00% Generic PainMar-1999Mon-20XX
72Lunesta Eszopiclone 225,1015.24% Generic InsomniaDec-2004April-2015
73Fenofibrate Fenofibrate 223,300-2.22% Generic CholesterolFeb-1998Mon-20XX
74Zytiga Abiraterone 222,02611.86% Janssen Biotech, Inc. Prostate CancerDec-1998April-2015
75Reyataz Atazanavir 217,793-1.38% Bristol-Myers Squibb HIV infectionJan-2003Mon-20XX
76Sensipar Cinacalcet 216,65713.71% Amgen Inc. HyperparathyroidismApr-2000Mon-20XX
77Metoprolol Metoprolol 215,1112.99% Generic HypertensionJan-1992Mon-20XX
78AcipHex Rabeprazole 214,25110.03% Janssen Pharmaceuticals, Inc, Johnson & Johnson Gastrointestinal disordersAug-1999Nov-2013
79Synthroid Levothyroxine 213,424-2.50% Generic HypothyroidismMay-1999Expired
80Avonex Pen Olmesartan 211,91713.59% Biogen Idec, Forest Laboratories HypertensionApr-2002Apr-2016
81Prevnar 13 Pneumococcal conjugate vaccine 209,3676.41% Pfizer Pneumococcal diseaseFeb-2000Jan-2007
82Xolair Omalizumab 207,8911.91% Genentech, Novartis Asthma2003Mon-20XX
83Lipitor Atorvastatin 207,5424.23% Generic CholesterolDec-1996Nov-2011 [11]
84levothyroxine Levothyroxine 204,7550.00% Generic HypothyroidismAug-1990Mon-20XX
85Benicar Olmesartan/hydrochlorothiazide 203,3363.22% Daiichi Sankyo HypertensionJun-1909Mon-2016
86Stribild Elvitegravir/cobicistat/emtricitabine/tenofovir 202,6420.00% Gilead Sciences HIV/AIDSApr-2000Mon-20XX [12]
87Zostavax Zostavax 202,24015.17% Eisai, Merck & Co. Herpes zosterAug-1999May-2013
88Pradaxa Dabigatran 200,697-0.53% Boehringer Ingelheim, Lilly Icos Oral anticoagulantOct-2010Mon-20XX
89Vytorin Ezetimibe/simvastatin 199,625-3.02% Merck & Co., Schering-Plough CholesterolJul-2004Mon-20XX
90Tamiflu Oseltamivir 197,7180.00% Chugai Pharmaceutical, Hetero Drugs, Roche InfluenzaOct-1999Mon-20XX
91Xgeva Denosumab 197,7113.24% Amgen OsteoporosisNov-2010Mon-20XX
92Evista Raloxifene 196,929-4.31% Eli Lilly and Company, Chugai Pharmaceutical OsteoporosisDec-1997Jan-2013
93Xeloda Capecitabine 194,0446.52% Generic CancerJun-1909Mon-20XX [13]
94Aranesp Darbepoetin alfa 185,225-9.22% Amgen Inc. AnemiaJun-2001Mon-20XX
95Ventolin HFA Salbutamol 183,0600.00% GlaxoSmithKline Asthma; chronic obstructive pulmonary diseaseMay-1981Mon-20XX
96divalproex sodium Valproate 181,5540.00% Generic Epilepsy and bipolar disorder [14] Jun-1909Mon-20XX
97Afinitor Everolimus 180,7190.03% Novartis CancerJun-1909Mon-20XX
98Betaseron, Betaferon Interferon beta 1b 179,216-3.72% Bayer Multiple sclerosisJul-1993Mon-20XX
99Adderall XR Amphetamine mixed salts 177,5053.31% Generic Attention deficit hyperactivity disorderOct-2001Mon-20XX
100Complera Emtricitabine/Rilpivirine/Tenofovir disoproxil fumarate 174,9330.00% Gilead Sciences, Inc. HIVJun-20XXMon-20XX

See also

Related Research Articles

An epinephrine autoinjector is a medical device for injecting a measured dose or doses of epinephrine (adrenaline) by means of autoinjector technology. It is most often used for the treatment of anaphylaxis. The first epinephrine autoinjector was brought to market in 1983.

<span class="mw-page-title-main">Generic drug</span> Pharmaceutical equivalent to a brand-name product

A generic drug is a pharmaceutical drug that contains the same chemical substance as a drug that was originally protected by chemical patents. Generic drugs are allowed for sale after the patents on the original drugs expire. Because the active chemical substance is the same, the medical profile of generics is equivalent in performance compared to their performance at the time when they were patented drugs. A generic drug has the same active pharmaceutical ingredient (API) as the original, but it may differ in some characteristics such as the manufacturing process, formulation, excipients, color, taste, and packaging.

<span class="mw-page-title-main">Infliximab</span> Biopharmaceutical drug for autoimmune disorders

Infliximab, a chimeric monoclonal antibody, sold under the brand name Remicade among others, is a medication used to treat a number of autoimmune diseases. This includes Crohn's disease, ulcerative colitis, rheumatoid arthritis, ankylosing spondylitis, psoriasis, psoriatic arthritis, and Behçet's disease. It is given by slow injection into a vein, typically at six- to eight-week intervals.

Etanercept, sold under the brand name Enbrel among others, is a biologic medical product that is used to treat autoimmune diseases by interfering with tumor necrosis factor (TNF), a soluble inflammatory cytokine, by acting as a TNF inhibitor. It has US Food and Drug Administration (FDA) approval to treat rheumatoid arthritis, juvenile idiopathic arthritis and psoriatic arthritis, plaque psoriasis and ankylosing spondylitis. Tumor necrosis factor alpha (TNFα) is the "master regulator" of the inflammatory (immune) response in many organ systems. Autoimmune diseases are caused by an overactive immune response. Etanercept has the potential to treat these diseases by inhibiting TNF-alpha.

<span class="mw-page-title-main">Gilead Sciences</span> American pharmaceutical company

Gilead Sciences, Inc. is an American biopharmaceutical company headquartered in Foster City, California that focuses on researching and developing antiviral drugs used in the treatment of HIV/AIDS, hepatitis B, hepatitis C, influenza, and COVID-19, including ledipasvir/sofosbuvir and sofosbuvir. Gilead is a member of the NASDAQ Biotechnology Index and the S&P 500.

<span class="mw-page-title-main">Piroxicam</span> Chemical compound

Piroxicam is a nonsteroidal anti-inflammatory drug (NSAID) of the oxicam class used to relieve the symptoms of painful inflammatory conditions like arthritis. Piroxicam works by preventing the production of endogenous prostaglandins which are involved in the mediation of pain, stiffness, tenderness and swelling. The medicine is available as capsules, tablets and, in some countries, as a prescription-free gel 0.5%. It is also available in a betadex formulation, which allows a more rapid absorption of piroxicam from the digestive tract. Piroxicam is one of the few NSAIDs that can be given parenteral routes.

Adalimumab, sold under the brand name Humira and others, is a disease-modifying antirheumatic drug and monoclonal antibody used to treat rheumatoid arthritis, juvenile idiopathic arthritis, psoriatic arthritis, ankylosing spondylitis, Crohn's disease, ulcerative colitis, plaque psoriasis, hidradenitis suppurativa, and uveitis. It is administered by subcutaneous injection. It works by inactivating tumor necrosis factor-alpha (TNFα).

<span class="mw-page-title-main">Celgene</span> American biopharmaceutical company

Celgene Corporation is a pharmaceutical company that makes cancer and immunology drugs. Its major product is Revlimid (lenalidomide), which is used in the treatment of multiple myeloma, and also in certain anemias. The company is incorporated in Delaware, headquartered in Summit, New Jersey, and a subsidiary of Bristol Myers Squibb (BMS).

<span class="mw-page-title-main">Apotex</span> Canadian pharmaceutical company

Apotex Inc. is a Canadian pharmaceutical corporation. Founded in 1974 by Barry Sherman, the company is the largest producer of generic drugs in Canada, with annual sales exceeding CA$2.5 billion. By 2023, Apotex employed close to 8,000 people as Canada's largest drug manufacturer, with over 300 products selling in over 115 countries. Apotex manufactures and distributes generic medications for a range of diseases and health conditions that include cancer, diabetes, high cholesterol, glaucoma, infections and blood pressure.

<span class="mw-page-title-main">Teva Pharmaceuticals</span> Israeli pharmaceutical company

Teva Pharmaceutical Industries Ltd. is an Israeli multinational pharmaceutical company. Teva specializes primarily in generic drugs, but other business interests include branded-drugs, active pharmaceutical ingredients (API's) and, to a lesser extent, contract manufacturing services and an out-licensing platform.

<span class="mw-page-title-main">Deflazacort</span> Pharmaceutical drug

Deflazacort is a glucocorticoid belonging to acetonides or O-isopropylidene derivative. It is used as an anti-inflammatory and was patented in 1969 and approved for medical use in 1985. The U.S. Food and Drug Administration (FDA) considers it to be a first-in-class medication for Duchenne Muscular Dystrophy.

<span class="mw-page-title-main">Golimumab</span> Pharmaceutical drug

Golimumab, sold under the brand name Simponi, is a human monoclonal antibody which is used as an immunosuppressive medication. Golimumab targets tumor necrosis factor alpha (TNF-alpha), a pro-inflammatory molecule and hence is a TNF inhibitor. Profound reduction in C-reactive protein (CRP) levels, interleukin (IL)-6, intercellaular adhesion molecules (ICAM)-1, matrix metalloproteinase (MMP)-3, and vascular endothelial growth factor (VEGF) demonstrates golimumab as an effective modulator of inflammatory markers and bone metabolism. Golimumab is given via subcutaneous injection.

Tocilizumab, sold under the brand name Actemra among others, is an immunosuppressive drug, used for the treatment of rheumatoid arthritis, systemic juvenile idiopathic arthritis, polyarticular juvenile idiopathic arthritis, giant cell arteritis, cytokine release syndrome, COVID‑19, and systemic sclerosis-associated interstitial lung disease (SSc-ILD). It is a humanized monoclonal antibody against the interleukin-6 receptor (IL-6R). Interleukin 6 (IL-6) is a cytokine that plays an important role in immune response and is implicated in the pathogenesis of many diseases, such as autoimmune diseases, multiple myeloma and prostate cancer. Tocilizumab was jointly developed by Osaka University and Chugai, and was licensed in 2003 by Hoffmann-La Roche.

<span class="mw-page-title-main">Tofacitinib</span> Medication

Tofacitinib, sold under the brand Xeljanz among others, is a medication used to treat rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, polyarticular course juvenile idiopathic arthritis, and ulcerative colitis. It is a janus kinase (JAK) inhibitor, discovered and developed by the National Institutes of Health and Pfizer.

<span class="mw-page-title-main">Secukinumab</span> Monoclonal antibody against IL-17

Secukinumab, sold under the brand name Cosentyx among others, is a human IgG1κ monoclonal antibody used for the treatment of psoriasis, ankylosing spondylitis, and psoriatic arthritis. It binds to the protein interleukin (IL)-17A and is marketed by Novartis.

Sarilumab, sold under the brand name Kevzara, is a human monoclonal antibody medication against the interleukin-6 receptor. Regeneron Pharmaceuticals and Sanofi developed the drug for the treatment of rheumatoid arthritis (RA), for which it received US FDA approval on 22 May 2017 and European Medicines Agency approval on 23 June 2017.

<span class="mw-page-title-main">Amneal Pharmaceuticals</span> American publicly traded generics and specialty pharmaceutical company

Amneal Pharmaceuticals, Inc. is an American publicly traded generics and specialty pharmaceutical company. The company is headquartered in Bridgewater, New Jersey.

Celltrion, Inc. is a biopharmaceutical company headquartered in Incheon, South Korea. Celltrion Healthcare conducts worldwide marketing, sales, and distribution of biological medicines developed by Celltrion. Celltrion's founder, Seo Jung-jin, is the richest person in South Korea.

<span class="mw-page-title-main">Adrenocorticotropic hormone (medication)</span> Chemical compound

Adrenocorticotropic hormone is used as a medication and as diagnostic agent in the ACTH stimulation test.

<span class="mw-page-title-main">Proprietary drug</span>

Proprietary drug are chemicals used for medicinal purposes which are formulated or manufactured under a name protected from competition through trademark or patent. The invented drug is usually still considered proprietary even if the patent expired. When a patent expires, generic drugs may be developed and released legally. Some international and national governmental organizations have set up laws to enforce intellectual property to protect proprietary drugs, but some also highlight the importance of public health disregarding legal regulations. Proprietary drugs affect the world in various aspects including medicine, public health and economy.

References

  1. ↑ "Top 15 Best-Selling Drugs of 2018". GEN - Genetic Engineering and Biotechnology News. 2019-03-11. Retrieved 2019-05-30.
  2. ↑ "The Top 15 Best-Selling Drugs of 2016". 6 March 2017.
  3. ↑ "Top drugs by sales revenue in 2015: Who sold the biggest blockbuster drugs?". March 10, 2016. Retrieved October 19, 2016.
  4. ↑ Drugs.com U.S. Pharmaceutical Sales - Q4 2013, updated Feb. 2014
  5. ↑ Patent Terms Extended Under 35 USC §156
  6. ↑ Orange Book Trade Name Search
  7. "Generic OxyContin Availability". Drugs.com.
  8. ↑ Unknown. "Generic Namenda Availability - Drugs.com". www.drugs.com. Drugs.com. Retrieved 21 December 2015.
  9. ↑ Donohue, Mark. "Impax Laboratories Inc. - Impax Launches Authorized Generic RENVELA®". investors.impaxlabs.com. Impax Laboratories. Retrieved 21 December 2015.
  10. Armstrong, Drew; Decker, Susan. "Pfizer's blockbuster blue pill Viagra set to go generic in 2015". Indianapolis Star. Retrieved 25 December 2015.
  11. ↑ "Atorvastatin: Drug Uses, Dosage, Side Effects - Drugs.com". www.drugs.com. drugs.com. Retrieved 21 December 2015.
  12. ↑ "HIV Treatment". www.stribild.com.
  13. ↑ Walsh, Sandy. "Press Announcements - FDA approves first generic capecitabine to treat colorectal and breast cancers". www.fda.gov. United States Food and Drug Administration. Retrieved 21 December 2015.
  14. ↑ "Valproic Acid". The American Society of Health-System Pharmacists. Archived from the original on 2017-07-31. Retrieved Oct 23, 2015.
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