Night monkeys, also known as owl monkeys or douroucoulis, are nocturnal New World monkeys of the genus Aotus, the only member of the family Aotidae. The genus comprises eleven species which are found across Panama and much of South America in primary and secondary forests, tropical rainforests and cloud forests up to 2,400 metres (7,900 ft). Night monkeys have large eyes which improve their vision at night, while their ears are mostly hidden, giving them their name Aotus, meaning "earless".
An HIV vaccine is a potential vaccine that could be either a preventive vaccine or a therapeutic vaccine, which means it would either protect individuals from being infected with HIV or treat HIV-infected individuals. It is thought that an HIV vaccine could either induce an immune response against HIV or consist of preformed antibodies against HIV.
The gray-bellied night monkey, also called the grey-legged douroucouli or lemurine owl monkey, is a small New World monkey of the family Aotidae. Native to tropical and subtropical forests of South America, the gray-bellied night monkey faces a significant threat from hunting, harvesting for use in pharmaceutical research and habitat destruction.
Labcorp Drug Development presently known as Fortrea is a contract research organization headquartered in Burlington, North Carolina, providing nonclinical, preclinical, clinical and commercialization services to pharmaceutical and biotechnology industries. Formerly called Covance, the company is a spin-off from Labcorp, which employs more than 70,000 people worldwide.
The brown spider monkey or variegated spider monkey is a critically endangered species of spider monkey, a type of New World monkey, from forests in northern Colombia and northwestern Venezuela.
Nancy Ma's night monkey is a night monkey species from South America. It is found in Brazil and Peru. The species is named after Dr. Nancy Shui-Fong Ma.
Texas Biomedical Research Institute, located in San Antonio, Texas, is an independent, non-profit biomedical research institution, specializing in genetics and in virology and immunology. Texas Biomed is funded by government and corporate grants and contracts, and donations from the public.
A synthetic vaccine is a vaccine consisting mainly of synthetic peptides, carbohydrates, or antigens. They are usually considered to be safer than vaccines from bacterial cultures. Creating vaccines synthetically has the ability to increase the speed of production. This is especially important in the event of a pandemic.
The history of animal testing goes back to the writings of the Ancient Greeks in the 4th and 3rd centuries BCE, with Aristotle and Erasistratus one of the first documented to perform experiments on nonhuman animals. Galen, a physician in 2nd-century Rome, dissected pigs and goats, and is known as the "Father of Vivisection." Avenzoar, an Arabic physician in 12th-century Moorish Spain who also practiced dissection, introduced animal testing as an experimental method of testing surgical procedures before applying them to human patients. Although the exact purpose of the procedure was unclear, a Neolithic surgeon performed trepanation on a cow in 3400-3000 BCE. This is the earliest known surgery to have been performed on an animal, and it is possible that the procedure was done on a dead cow in order for the surgeon to practice their skills.
Experiments involving non-human primates (NHPs) include toxicity testing for medical and non-medical substances; studies of infectious disease, such as HIV and hepatitis; neurological studies; behavior and cognition; reproduction; genetics; and xenotransplantation. Around 65,000 NHPs are used every year in the United States, and around 7,000 across the European Union. Most are purpose-bred, while some are caught in the wild.
Animal Defenders International (ADI), founded 1990, has offices in US, UK, Colombia, Peru and South Africa; it actuates education and public awareness campaigns to protect animals in captivity and wild animals and their environments. ADI 's campaigns focus on animals used in entertainment, sport, for clothing; illegal wildlife trade; and replacement of animals used in research and testing. ADI collaborates with governments on large-scale international rescues of wild animals following legislation to end animal circuses, illegal animal trafficking. ADI owns and operates the ADI Wildlife Sanctuary, South Africa, home to nearly 40 ex-circus lions and tigers from Peru, Colombia and Guatemala.
Malaria vaccines are vaccines that prevent malaria, a mosquito-borne infectious disease which affected an estimated 249 million people globally in 85 malaria endemic countries and areas and caused 608,000 deaths in 2022. The first approved vaccine for malaria is RTS,S, known by the brand name Mosquirix. As of April 2023, the vaccine has been given to 1.5 million children living in areas with moderate-to-high malaria transmission. It requires at least three doses in infants by age 2, and a fourth dose extends the protection for another 1–2 years. The vaccine reduces hospital admissions from severe malaria by around 30%.
Immunocontraception is the use of an animal's immune system to prevent it from fertilizing offspring. Contraceptives of this type are not currently approved for human use.
The gray-handed night monkey is a species of night monkey formerly considered a subspecies of Gray-bellied night monkey of the family Aotidae. Its range consists of parts of Colombia and Venezuela. The exact classification of the gray-handed night monkey is uncertain. While some authors consider it a subspecies of the gray-bellied night monkey, A. lemurinus, other authors consider it a separate species, A. griseimembra.
Naval Medical Research Unit SOUTH, formerly known as Naval Medical Research Unit Six, is a biomedical research laboratory of the U.S. Navy located in Lima, Peru. It is the only U.S. military command located in South America. Its mission is to identify infectious disease threats of military and public health importance and to develop and evaluate interventions and products to mitigate those threats.
Hospital San Juan de Dios in Bogotá housed the National Institute of Immunology where important research on vaccines, notably the first synthetic vaccine against malaria, was conducted, The Instituto Meterno-infantil, Hospital La Hortúa and the Santa Clara Clinic currently. It is one of the oldest serving hospitals in Latin America. It was founded in 1723 in times of the colony, yet its operation dates back the 1564 and was called Hospital de San Pedro and was established with the properties donated by Bishop Juan de los Barrios. It was later called Hospital de Jesús, José y María and finally Hospital San Juan de Dios. It initially consisted of three buildings of republican architectural style. The main building was modeled after the Pasteur Institute in France. and was finished in 1921. Later, a 1960 style high-rise building was constructed to house the hospital, and the original buildings were left abandoned.
The immunome is the set of genes that code for proteins which constitute the immune system, excluding those that are widespread in other cell types, and not involved in the immune response itself. It is further defined as the set of peptides derived from the proteome that interact with the immune system. There are numerous ongoing efforts to characterize and sequence the immunomes of humans, mice, and elements of non-human primates. Typically, immunomes are studied using immunofluorescence microscopy to determine the presence and activity of immune-related enzymes and pathways. Practical applications for studying the immunome include vaccines, therapeutic proteins, and further treatment of other diseases. The study of the immunome falls under the field of immunomics.
Plasmodium brasilianum is a parasite that infects many species of platyrrhine monkeys in South and Central America.
S-268019-b is a protein subunit COVID-19 vaccine candidate developed by Shionogi.
