Metanephrines

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Norepinephrine breakdown, with normetanephrine visible at upper left. Noradrenaline breakdown.svg
Norepinephrine breakdown, with normetanephrine visible at upper left.

The metanephrines are a group of molecules consisting of metanephrine and normetanephrine.

An article in the Journal of the American Medical Association , 2002, indicated that the measurement of plasma free levels of metanephrines is the best tool in the diagnosis of pheochromocytoma, an adrenal medullary neoplasm. [1]

References

  1. Lenders J, Pacak K, Walther M, Linehan W, Mannelli M, Friberg P, Keiser H, Goldstein D, Eisenhofer G (2002). "Biochemical diagnosis of pheochromocytoma: which test is best?". JAMA. 287 (11): 1427–34. doi: 10.1001/jama.287.11.1427 . PMID   11903030. Free full text with registration