Normetanephrine

Last updated
Normetanephrine
Normetanephrine.svg
Names
IUPAC name
4-(2-amino-1-hydroxy-ethyl)- 2-methoxy-phenol
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
MeSH Normetanephrine
PubChem CID
UNII
  • InChI=1S/C9H13NO3/c1-13-9-4-6(8(12)5-10)2-3-7(9)11/h2-4,8,11-12H,5,10H2,1H3 Yes check.svgY
    Key: YNYAYWLBAHXHLL-UHFFFAOYSA-N Yes check.svgY
  • InChI=1/C9H13NO3/c1-13-9-4-6(8(12)5-10)2-3-7(9)11/h2-4,8,11-12H,5,10H2,1H3
    Key: YNYAYWLBAHXHLL-UHFFFAOYAR
  • Oc1ccc(cc1OC)C(O)CN
Properties
C9H13NO3
Molar mass 183.204 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Normetanephrine, also called normetadrenaline, [1] is a metabolite of norepinephrine created by action of catechol-O-methyl transferase on norepinephrine. It is excreted in the urine and found in certain tissues. It is a marker for catecholamine-secreting tumors such as pheochromocytoma.

Norepinephrine degradation. Normetanephrine is shown at top left. Enzymes are shown in boxes. Noradrenaline breakdown.svg
Norepinephrine degradation. Normetanephrine is shown at top left. Enzymes are shown in boxes.

References

  1. ↑ "Human Metabolome Database: Showing metabocard for Normetanephrine (HMDB0000819)". hmdb.ca. Retrieved 2023-11-17.
  2. ↑ Figure 11-4 in: Flower, R.; Rang, H. P.; Dale, M. M.; Ritter, J. M. (2007). Rang & Dale's Pharmacology. Edinburgh: Churchill Livingstone. ISBN   978-0-443-06911-6.


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