4-Methylphenmetrazine

4-Methylphenmetrazine

Identifiers
IUPAC name 3-methyl-2-(4-methylphenyl)morpholine
CAS Number	1094649-71-4 1998216-41-3 (Hydrochloride)
PubChem CID	43169333
ChemSpider	27935395
UNII	V88J79BT5J
CompTox Dashboard (EPA)	DTXSID001336886
Chemical and physical data
Formula	C12H17NO
Molar mass	191.274 g·mol−1
3D model (JSmol)	Interactive image
SMILES CC1C(OCCN1)C2=CC=C(C=C2)C
InChI InChI=1S/C12H17NO/c1-9-3-5-11(6-4-9)12-10(2)13-7-8-14-12/h3-6,10,12-13H,7-8H2,1-2H3 Key:NWNCIXFIIDVRKE-UHFFFAOYSA-N

4-Methylphenmetrazine (mephenmetrazine, 4-MPM, PAL-747) is a recreational designer drug with stimulant effects. It is a substituted phenylmorpholine derivative, closely related to better known drugs such as phenmetrazine and 3-fluorophenmetrazine. It was first identified in Slovenia in 2015, ^{[1] [2]} and has been shown to act as a monoamine releaser with some preference for serotonin release. ^{[3] [4]}

See also

• 4,4'-DMAR
• 4-Methylamphetamine
• 4-Methylmethylphenidate
• G-130
• Mephedrone
• RTI-32
• Phendimetrazine
• PDM-35

References

1. "Analytical Report. 4-MPH (C12H17NO) 3-methyl-2(p-tolyl)morpholine" (PDF). National Forensic Laboratory. Slovenia. 14 October 2015.
2. "Europol 2015 Annual Report on the implementation of Council Decision 2005/387/JHA" (PDF). The European Monitoring Centre for Drugs and Drug Addiction (EMCDDA) & Europol.
3. US 20130203752,Blough BE, Rothman R, Landavazo A, Page KM, Decker AM,"Phenylmorpholines and analogues thereof",published 8 August 2013,issued 11 April 2017, assigned to National Institutes of Health, U.S. Department of Health and Human Services 
4. McLaughlin G, Baumann MH, Kavanagh PV, Morris N, Power JD, Dowling G, et al. (September 2018). "Synthesis, analytical characterization, and monoamine transporter activity of the new psychoactive substance 4-methylphenmetrazine (4-MPM), with differentiation from its ortho- and meta- positional isomers". Drug Testing and Analysis. 10 (9): 1404–1416. doi:10.1002/dta.2396. PMC   7316143 . PMID   29673128.