Phenylpiracetam hydrazide

Phenylpiracetam hydrazide

Clinical data
Trade names	Phenylpiracetam hydrazide
Other names	Fonturacetam hydrazide
Pregnancy category	Unknown
Routes of administration	Oral
ATC code	none
Legal status
Legal status	US:Not FDA approved; unscheduled
Identifiers
IUPAC name 2-(2-oxo-4-phenylpyrrolidin-1-yl)acetohydrazide
CAS Number	77472-71-0
PubChem CID	4995664
ChemSpider	4175636  Y
UNII	289199VKN4
CompTox Dashboard (EPA)	DTXSID001032563
Chemical and physical data
Formula	C12H15N3O2
Molar mass	233.271 g·mol−1
3D model (JSmol)	Interactive image
Chirality	Racemic mixture
SMILES c1ccc(cc1)C2CC(=O)N(C2)CC(=O)NN
InChI InChI=1S/C12H15N3O2/c13-14-11(16)8-15-7-10(6-12(15)17)9-4-2-1-3-5-9/h1-5,10H,6-8,13H2,(H,14,16) Y Key:AXQUMNYYLGUJIZ-UHFFFAOYSA-N Y
NY  (what is this?)    (verify)

Phenylpiracetam hydrazide, also known as fonturacetam hydrazide, ^[1] is a racetam that is a derivative of phenylpiracetam in which the amide group is replaced with a hydrazide group. It was first reported by a Russian research group in 1980 as part of a series of chemical compounds investigated as anticonvulsants. ^[2] In an electroshock test it was found to have an ED₅₀ of 310 mg/kg. ^[2]

Sale on the internet

All piracetam derivatives are not permitted to be sold as dietary supplements in the United States. ^[3] However, because they lack scheduling, piracetam derivatives like phenylpiracetam hydrazide are sold over the clear net accompanied by indications stating that the compound is "not for human consumption". ^[4]

See also

• Piracetam
• List of Russian drugs

References

1. "International Nonproprietary Names for Pharmaceutical Substances (INN). Recommended International Nonproprietary Names: List 63" (PDF). WHO Drug Information. 24 (1): 56. 2010. Archived from the original (PDF) on May 21, 2014. Retrieved 26 November 2015.
2. Glozman OM, Morozov IS, Zhmurenko LA, Zagorevskii VA (1980). "Synthesis and anticonvulsive activity of 4-phenyl-2-pyrrolidinone-1-acetic acid amides". Khimiko-Farmatsevticheskii Zhurnal (in Russian). 14 (11): 43–48.
3. Cohen PA, Zakharevich I, Gerona R (March 2020). "Presence of Piracetam in Cognitive Enhancement Dietary Supplements". JAMA Internal Medicine. 180 (3): 458–459. doi:10.1001/jamainternmed.2019.5507. PMC   6902196 . PMID   31764936. S2CID   208274670.
4. Musselman ME, Hampton JP (July 2014). ""Not for human consumption": a review of emerging designer drugs". Pharmacotherapy. 34 (7): 745–757. doi: 10.1002/phar.1424 . PMID   24710806. S2CID   10279777.