Dupracetam

Dupracetam

Clinical data
ATC code	none
Legal status
Legal status	In general: unscheduled
Identifiers
IUPAC name 2-(2-oxopyrrolidin-1-yl)-N'-[2-(2-oxopyrrolidin-1-yl)acetyl]acetohydrazide
CAS Number	59776-90-8  Y
PubChem CID	68793
ChemSpider	62033  N
UNII	BVM2UGN450
ChEMBL	ChEMBL2104359  N
CompTox Dashboard (EPA)	DTXSID40975187
ECHA InfoCard	100.056.279
Chemical and physical data
Formula	C12H18N4O4
Molar mass	282.300 g·mol−1
3D model (JSmol)	Interactive image
SMILES C1CC(=O)N(C1)CC(=O)NNC(=O)CN2CCCC2=O
InChI InChI=1S/C12H18N4O4/c17-9(7-15-5-1-3-11(15)19)13-14-10(18)8-16-6-2-4-12(16)20/h1-8H2,(H,13,17)(H,14,18) N Key:YPUPYVWSTBYCBY-UHFFFAOYSA-N N
NY  (what is this?)    (verify)

Dupracetam is a nootropic drug from the racetam family. ^{[1] [2]}

One of its metabolites, 1-Methylhydantoin, displays renal toxicity in high doses. ^[3]

See also

• Piracetam

References

1. Dell HD, Jacobi H, Kamp R, Kurz J, Wünsche C (August 1981). "[1-Methylhydantoin, an unexpected metabolite of the intelligence-affecting substance dupracetam (author's transl)]". Archiv der Pharmazie (in German). 314 (8): 697–702. doi:10.1002/ardp.19813140808. PMID   7294979. S2CID   95603731.
2. Hall ED, Von Voigtlander PF (November 1987). "Facilitatory effects of piracetam on excitability of motor nerve terminals and neuromuscular transmission". Neuropharmacology. 26 (11): 1573–1579. doi:10.1016/0028-3908(87)90003-7. PMID   2829047. S2CID   7759558.
3. Yang B, Liu D, Li CZ, Liu FY, Peng YM, Jiang YS (2007). "1-Methylhydantoin cytotoxicity on renal proximal tubular cells in vitro". Renal Failure. 29 (8): 1025–1029. doi: 10.1080/08860220701641272 . PMID   18067051. S2CID   26843776.