Psychotropic alkylamines are alkylamines that share the critical property of not containing an aromatic nucleus, but are still biologically active. While many of these molecules are stimulants, others are antiviral, have competitive NMDA antagonist activity, or are nicotinic receptor antagonists.
| Compound | Core | Other | N Substituent | Pharmacology |
|---|---|---|---|---|
| Neramexane | Cyclohexyl | 1,3,3,5,5-Pentamethyl | 1-NH2 | NMDA receptor antagonist [1] |
| Amantadine | adamantane | — | 1-NH2 | antiviral, NMDA antagonist, catecholamine releaser, cholinergic |
| Memantine | " | 3,5-DiMe | " | NMDA antagonist |
| Rimantadine | " | CH3CH | NH2 | antiviral |
| Cyclopentamine | cyclopentane | n-propyl | 2-NHMe | Sympathomimetic vasoconstrictor |
| Propylhexedrine | cyclohexane | " | " | " |
| Methylhexanamine | n-hexane | 4-methyl | 2-NH2 | " |
| Tuaminoheptane | n-heptane | — | 2-NH2 | " |
| Octodrine | " | 6-methyl | " | " |
| Mecamylamine | norbornane | 1-exo-2,2-trimethyl | 1-endo-NHMe | nicotinic antagonist |