Dibenzodiazepine

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Clozapine, an antipsychotic and example of a dibenzodiazepine. Clozapine.svg
Clozapine, an antipsychotic and example of a dibenzodiazepine.

A dibenzodiazepine, also known as a dibenzo[b,e][1,4]diazepine, is a tricyclic chemical compound. [2] Derivatives of dibenzodiazepine, or substituted dibenzodiazepines, include the antipsychotic clozapine, [1] the antihistamine clobenzepam, and the tricyclic antidepressant dibenzepin, [3] among others. [4]

References

  1. 1 2 Wenthur CJ, Lindsley CW (July 2013). "Classics in chemical neuroscience: clozapine". ACS Chem Neurosci. 4 (7): 1018–1025. doi:10.1021/cn400121z. PMC   3715841 . PMID   24047509.
  2. "Dibenzo[b,e][1,4]diazepine". PubChem. Retrieved 30 March 2025.
  3. Marxer A, Schier O (1976). "Fundamental structures in drug research". Prog Drug Res. 20: 385–432. doi:10.1007/978-3-0348-7094-8_12. PMID   13461.
  4. Liegeois, J. F., Bruhwyler, J., Rogister, F., & Delarge, J. (1995). Diarylazepine derivatives as potent atypical neuroleptic drugs: recent advances. Current Medicinal Chemistry, 1(6), 471–501. https://books.google.com/books?id=eMw2LsjQ5PQC&pg=PA471