Deptropine

Deptropine

Clinical data
ATC code	R06AX16 ( WHO )
Identifiers
IUPAC name 3a-[(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-yl) oxy]1aH,5aH-tropane
CAS Number	604-51-3 2169-75-7
PubChem CID	16576
DrugBank	DB13466
ChemSpider	16735768  Y
UNII	AY31301GKG
KEGG	D07404  Y
ChEBI	CHEBI:50189  Y
ChEMBL	ChEMBL1946186
CompTox Dashboard (EPA)	DTXSID5048556
ECHA InfoCard	100.009.154
Chemical and physical data
Formula	C23H27NO
Molar mass	333.475 g·mol−1
3D model (JSmol)	Interactive image
SMILES CN5[C@@H]1CC[C@H]5C[C@H](C1)OC3c4ccccc4CCc2ccccc23
InChI InChI=1S/C23H27NO/c1-24-18-12-13-19(24)15-20(14-18)25-23-21-8-4-2-6-16(21)10-11-17-7-3-5-9-22(17)23/h2-9,18-20,23H,10-15H2,1H3/t18-,19+,20+ Y Key:ZWPODSUQWXAZNC-PMOLBWCYSA-N Y
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Deptropine (Brontina) also known as dibenzheptropine, is an antihistamine with anticholinergic properties acting at the H1 receptor. ^[1] It is usually marketed as the citrate salt. ^[2]

References

1. PubChem. "Deptropine". pubchem.ncbi.nlm.nih.gov. Retrieved 2020-11-16.
2. Leckie WJ, Horne NW (July 1965). "Preliminary Assessment of Deptropine Dihydrogen Citrate in Chronic Airways Obstruction". Thorax. 20 (4): 317–23. doi:10.1136/thx.20.4.317. PMC   1018942 . PMID   14321719.