4-Methylhistamine

Last updated
4-Methylhistamine
4-Methylhistamine.svg
Names
Preferred IUPAC name
2-(5-Methyl-1H-imidazol-4-yl)ethan-1-amine
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
ECHA InfoCard 100.163.601 OOjs UI icon edit-ltr-progressive.svg
KEGG
MeSH 4-methylhistamine
PubChem CID
UNII
  • InChI=1S/C6H11N3/c1-5-6(2-3-7)9-4-8-5/h4H,2-3,7H2,1H3,(H,8,9) Yes check.svgY
    Key: UGYXPZQILZRKJJ-UHFFFAOYSA-N Yes check.svgY
  • InChI=1/C6H11N3/c1-5-6(2-3-7)9-4-8-5/h4H,2-3,7H2,1H3,(H,8,9)
    Key: UGYXPZQILZRKJJ-UHFFFAOYAJ
  • CC1=C(N=CN1)CCN
Properties
C6H11N3
Molar mass 125.17164 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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4-Methylhistamine is a histamine agonist selective for the H4 subtype. [1]

References

  1. ↑ Lim HD, van Rijn RM, Ling P, Bakker RA, Thurmond RL, Leurs R (September 2005). "Evaluation of histamine H1-, H2-, and H3-receptor ligands at the human histamine H4 receptor: identification of 4-methylhistamine as the first potent and selective H4 receptor agonist". J. Pharmacol. Exp. Ther. 314 (3): 1310–21. doi:10.1124/jpet.105.087965. PMID   15947036. S2CID   24248896.
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