Clinical data  

Synonyms  Neohetramine 
AHFS/Drugs.com  International Drug Names 
ATC code  
Identifiers  
 
CAS Number  
PubChem CID  
ChemSpider 

UNII  
KEGG 

ChEMBL 

CompTox Dashboard (EPA)  
ECHA InfoCard  100.001.913 
Chemical and physical data  
Formula  C_{16}H_{22}N_{4}O 
Molar mass  286.372 g/mol g·mol^{−1} 
3D model (JSmol)  
 
 
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Thonzylamine (or neohetramine)^{ [1] } is an antihistamine and anticholinergic used as an antipruritic.
Antihistamines are drugs which treat allergic rhinitis and other allergies. Typically people take antihistamines as an inexpensive, generic, overthecounter drug that can provide relief from nasal congestion, sneezing, or hives caused by pollen, dust mites, or animal allergy with few side effects. Antihistamines are usually for shortterm treatment. Chronic allergies increase the risk of health problems which antihistamines might not treat, including asthma, sinusitis, and lower respiratory tract infection. Consultation of a medical professional is recommended for those who intend to take antihistamines for longerterm use.
An anticholinergic agent is a substance that blocks the neurotransmitter acetylcholine in the central and the peripheral nervous system. These agents inhibit parasympathetic nerve impulses by selectively blocking the binding of the neurotransmitter acetylcholine to its receptor in nerve cells. The nerve fibers of the parasympathetic system are responsible for the involuntary movement of smooth muscles present in the gastrointestinal tract, urinary tract, lungs, and many other parts of the body. Anticholinergics are divided into three categories in accordance with their specific targets in the central and peripheral nervous system: antimuscarinic agents, ganglionic blockers, and neuromuscular blockers.
Antipruritics, also known as antiitch drugs, are medications that inhibit the itching often associated with sunburns, allergic reactions, eczema, psoriasis, chickenpox, fungal infections, insect bites and stings like those from mosquitoes, fleas, and mites, and contact dermatitis and urticaria caused by plants such as poison ivy or stinging nettle.
In linear algebra, the determinant is a scalar value that can be computed from the elements of a square matrix and encodes certain properties of the linear transformation described by the matrix. The determinant of a matrix A is denoted det(A), det A, or A. Geometrically, it can be viewed as the volume scaling factor of the linear transformation described by the matrix. This is also the signed volume of the ndimensional parallelepiped spanned by the column or row vectors of the matrix. The determinant is positive or negative according to whether the linear mapping preserves or reverses the orientation of nspace.
In physics, the electronvolt is a unit of energy equal to exactly 1.602176634×10^{−19} joules in SI units.
Felidae is a family of mammals in the order Carnivora, colloquially referred to as cats, and constitute a clade. A member of this family is also called a felid. The term "cat" refers both to felids in general and specifically to the domestic cat.
In mathematics, a Taylor series is a representation of a function as an infinite sum of terms that are calculated from the values of the function's derivatives at a single point.
Electrical impedance is the measure of the opposition that a circuit presents to a current when a voltage is applied. The term complex impedance may be used interchangeably.
In mathematics, the quaternions are a number system that extends the complex numbers. They were first described by Irish mathematician William Rowan Hamilton in 1843 and applied to mechanics in threedimensional space. A feature of quaternions is that multiplication of two quaternions is noncommutative. Hamilton defined a quaternion as the quotient of two directed lines in a threedimensional space or equivalently as the quotient of two vectors.
In machine learning, supportvector machines are supervised learning models with associated learning algorithms that analyze data used for classification and regression analysis. Given a set of training examples, each marked as belonging to one or the other of two categories, an SVM training algorithm builds a model that assigns new examples to one category or the other, making it a nonprobabilistic binary linear classifier. An SVM model is a representation of the examples as points in space, mapped so that the examples of the separate categories are divided by a clear gap that is as wide as possible. New examples are then mapped into that same space and predicted to belong to a category based on which side of the gap they fall.
Hepatitis C is an infectious disease caused by the hepatitis C virus (HCV) that primarily affects the liver. During the initial infection people often have mild or no symptoms. Occasionally a fever, dark urine, abdominal pain, and yellow tinged skin occurs. The virus persists in the liver in about 75% to 85% of those initially infected. Early on chronic infection typically has no symptoms. Over many years however, it often leads to liver disease and occasionally cirrhosis. In some cases, those with cirrhosis will develop serious complications such as liver failure, liver cancer, or dilated blood vessels in the esophagus and stomach.
In mathematics and vector algebra, the cross product or vector product is a binary operation on two vectors in threedimensional space and is denoted by the symbol . Given two linearly independent vectors and , the cross product, , is a vector that is perpendicular to both and and thus normal to the plane containing them. It has many applications in mathematics, physics, engineering, and computer programming. It should not be confused with the dot product.
Heat capacity or thermal capacity is a physical property of a material object, defined as the amount of energy that must be added to the object in order to achieve a small change in its temperature, divided by the magnitude of that change. Informally, it is the amount of heat energy that must be provided to the object in order to uniformly raise its temperature by one unit.
In mathematics, summation is the addition of a sequence of any kind of numbers, called addends or summands; the result is their sum or total. Besides numbers, other types of values can be summed as well: functions, vectors, matrices, polynomials and, in general, elements of any types of mathematical objects on which an operation denoted "+" is defined.
J. C. Penney Company, Inc. is an American department store chain with 864 locations in 49 U.S. states and Puerto Rico. In addition to selling conventional merchandise, J. C. Penney stores often house several leased departments such as Sephora, Seattle's Best Coffee, salons, auto centers, optical centers, portrait studios, and jewelry repair.
In statistics, originally in geostatistics, kriging or Gaussian process regression is a method of interpolation for which the interpolated values are modeled by a Gaussian process governed by prior covariances. Under suitable assumptions on the priors, kriging gives the best linear unbiased prediction of the intermediate values. Interpolating methods based on other criteria such as smoothness need not yield the most likely intermediate values. The method is widely used in the domain of spatial analysis and computer experiments. The technique is also known as Wiener–Kolmogorov prediction, after Norbert Wiener and Andrey Kolmogorov.
ATC code D04Antipruritics, including antihistamines, anesthetics, etc. is a therapeutic subgroup of the Anatomical Therapeutic Chemical Classification System, a system of alphanumeric codes developed by the WHO for the classification of drugs and other medical products. Subgroup D04 is part of the anatomical group D Dermatologicals.
ATC code R06Antihistamines for systemic use is a therapeutic subgroup of the Anatomical Therapeutic Chemical Classification System, a system of alphanumeric codes developed by the WHO for the classification of drugs and other medical products. Subgroup R06 is part of the anatomical group R Respiratory system.
The Lockheed Martin C130J Super Hercules is a fourengine turboprop military transport aircraft. The C130J is a comprehensive update of the Lockheed C130 Hercules, with new engines, flight deck, and other systems. The Hercules family has the longest continuous production run of any military aircraft in history. During more than 60 years of service, the family has participated in military, civilian, and humanitarian aid operations. The Hercules has outlived several planned successor designs, most notably the Advanced Medium STOL Transport contestants. As of February 2018, 400 C130J aircraft have been delivered to 17 nations.
Alzheimer's disease (AD), also referred to simply as Alzheimer's, is a chronic neurodegenerative disease that usually starts slowly and gradually worsens over time. It is the cause of 60–70% of cases of dementia. The most common early symptom is difficulty in remembering recent events. As the disease advances, symptoms can include problems with language, disorientation, mood swings, loss of motivation, not managing self care, and behavioural issues. As a person's condition declines, they often withdraw from family and society. Gradually, bodily functions are lost, ultimately leading to death. Although the speed of progression can vary, the typical life expectancy following diagnosis is three to nine years.
Diffusion is net movement of anything from a region of higher concentration to a region of lower concentration. Diffusion is driven by a gradient in concentration.
Zolamine is an antihistamine and anticholinergic used as an antipruritic.
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