Prifinium bromide

Prifinium bromide
Clinical data
AHFS/Drugs.com	International Drug Names
ATC code	A03AB18 ( WHO );
Identifiers
	IUPAC name 3-(Diphenylmethylene)-1,1-diethyl-2-methylpyrrolidinium bromide;
CAS Number	4630-95-9 ;
PubChem CID	20749 ;
ChemSpider	19537 ;
UNII	3B7O9ZC520 ;
ChEMBL	ChEMBL1213353 ;
CompTox Dashboard (EPA)	DTXSID3023508 ;
ECHA InfoCard	100.022.774
Chemical and physical data
Formula	C22H28BrN
Molar mass	386.377 g·mol−1
	InChI InChI=1S/C22H28N.BrH/c1-4-23(5-2)17-16-21(18(23)3)22(19-12-8-6-9-13-19)20-14-10-7-11-15-20;/h6-15,18H,4-5,16-17H2,1-3H3;1H/q+1;/p-1 ; Key:UCGJZJXOPSNTGZ-UHFFFAOYSA-M ;
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Last updated January 01, 2026

Prifinium bromide is a pharmaceutical drug used primarily in the treatment of irritable bowel syndrome due to its action as an anticholinergic.^[1]

Prifinium bromide's mechanism of action is believed to be due to its activity as an antispasmodic agent.^[2]

Prifinium bromide is an antimuscarinic.^[3]

References

↑ Piai, Guido (1975). "[Prifinium bromide in the treatment of the irritable colon syndrome]". Gastroenterology. 77 (3): 500–502. doi:10.1016/0016-5085(79)90012-X. PMID 37142.
↑ Silber W (1979). "[Prifinium bromide-a new antispasmodic.]". South African Medical Journal. 56 (24): 1033–1034. PMID 45057.
↑ Magalini M, Monica F (June 1995). "[Use of prifinium bromide in endoscopic premedication. A double-blind controlled study vs hyoscine N-butylbromide]". Minerva Gastroenterologica e Dietologica. 41 (2): 197–202. PMID 7647144.

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[1] Piai, Guido (1975). "[Prifinium bromide in the treatment of the irritable colon syndrome]". Gastroenterology. 77 (3): 500–502. doi:10.1016/0016-5085(79)90012-X. PMID 37142.

[2] Silber W (1979). "[Prifinium bromide-a new antispasmodic.]". South African Medical Journal. 56 (24): 1033–1034. PMID 45057.

[3] Magalini M, Monica F (June 1995). "[Use of prifinium bromide in endoscopic premedication. A double-blind controlled study vs hyoscine N-butylbromide]". Minerva Gastroenterologica e Dietologica. 41 (2): 197–202. PMID 7647144.

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