Benzilone

Benzilone
Clinical data
ATC code	A03AB01 ( WHO );
Identifiers
	IUPAC name 1,1-diethyl-3-(2-hydroxy-2,2-diphenylacetoxy)pyrrolidinium;
CAS Number	16175-92-1 ; 1050-48-2 (bromide);
PubChem CID	66248 ;
ChemSpider	59632 ;
UNII	GY56LQX77B ;
ChEMBL	ChEMBL2106061 ;
CompTox Dashboard (EPA)	DTXSID40859574 ;
Chemical and physical data
Formula	C22H28NO3
Molar mass	354.470 g·mol−1
3D model (JSmol)	Interactive image ;
	SMILES O=C(OC1CC[N+](CC)(CC)C1)C(O)(c2ccccc2)c3ccccc3;
	InChI InChI=1S/C22H28NO3/c1-3-23(4-2)16-15-20(17-23)26-21(24)22(25,18-11-7-5-8-12-18)19-13-9-6-10-14-19/h5-14,20,25H,3-4,15-17H2,1-2H3/q+1 ; Key:ZKCWITXZGWUJAV-UHFFFAOYSA-N ;
	(what is this?) (verify)

Last updated April 29, 2025

Benzilone is an antimuscarinic drug.^[1]^[2]

References

↑ "Benzilone". KEGG database. Retrieved 9 May 2015.
↑ Schwartz TW, Stenquist B, Olbe L, Stadil F (January 1979). "Synchronous oscillations in the basal secretion of pancreatic-polypeptide and gastric acid. Depression by cholinergic blockade of pancreatic-polypeptide concentrations in plasma". Gastroenterology. 76 (1): 14–9. doi: 10.1016/s0016-5085(79)80121-3 . PMID 758136. Benzilonium bromide (Parke, Davis & Co., Detroit Mich.) is a quarternary [sic] antimuscarinic agent with minimal passage of the blood-brain barrier.

This drug article relating to the gastrointestinal system is a stub. You can help Wikipedia by expanding it.

This page is based on this Wikipedia article
Text is available under the CC BY-SA 4.0 license; additional terms may apply.
Images, videos and audio are available under their respective licenses.

[1] "Benzilone". KEGG database. Retrieved 9 May 2015.

[Schwartz_1979-2] Schwartz TW, Stenquist B, Olbe L, Stadil F (January 1979). "Synchronous oscillations in the basal secretion of pancreatic-polypeptide and gastric acid. Depression by cholinergic blockade of pancreatic-polypeptide concentrations in plasma". Gastroenterology. 76 (1): 14–9. doi: 10.1016/s0016-5085(79)80121-3 . PMID 758136. Benzilonium bromide (Parke, Davis & Co., Detroit Mich.) is a quarternary [sic] antimuscarinic agent with minimal passage of the blood-brain barrier.

[1]

[2]

Clinical data

ATC code	A03AB01 ( WHO )
Identifiers
IUPAC name 1,1-diethyl-3-(2-hydroxy-2,2-diphenylacetoxy)pyrrolidinium
CAS Number	16175-92-1 ^Y 1050-48-2 (bromide)
PubChem CID	66248
ChemSpider	59632 ^N
UNII	GY56LQX77B
ChEMBL	ChEMBL2106061 ^N
CompTox Dashboard (EPA)	DTXSID40859574
Chemical and physical data
Formula	C₂₂H₂₈NO₃
Molar mass	354.470 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES O=C(OC1CC[N+](CC)(CC)C1)C(O)(c2ccccc2)c3ccccc3
InChI InChI=1S/C22H28NO3/c1-3-23(4-2)16-15-20(17-23)26-21(24)22(25,18-11-7-5-8-12-18)19-13-9-6-10-14-19/h5-14,20,25H,3-4,15-17H2,1-2H3/q+1^N Key:ZKCWITXZGWUJAV-UHFFFAOYSA-N^N
^NY (what is this?) (verify)