Losindole

Losindole
Clinical data
Routes of; administration	Oral
ATC code	none;
Legal status
Legal status	In general: uncontrolled;
Identifiers
	IUPAC name (3aS,4R,9aR)-6-chloro-2-methyl-4-phenyl-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]isoindole;
CAS Number	69175-77-5 ;
PubChem CID	3045392 ;
ChemSpider	2308134 ;
UNII	IX8TM6153H ;
CompTox Dashboard (EPA)	DTXSID50219221 ;
Chemical and physical data
Formula	C19H20ClN
Molar mass	297.83 g·mol−1
3D model (JSmol)	Interactive image ;
	SMILES Clc1ccc3c(c1)[C@@H](c2ccccc2)[C@H]4[C@@H](C3)CN(C4)C;

Last updated January 04, 2023

Losindole (BI-27,062) is an antidepressant with a tetracyclic structure.^[1] It was never marketed.^[1]

References

1 2 Triggle, David J. (1996). Dictionary of Pharmacological Agents. Boca Raton: Chapman & Hall/CRC. ISBN 0-412-46630-9.

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[Triggle1997-1] 1 2 Triggle, David J. (1996). Dictionary of Pharmacological Agents. Boca Raton: Chapman & Hall/CRC. ISBN 0-412-46630-9.

[1]

v t e Anxiolytics (N05B)
5-HT_1AR agonists	Buspirone Gepirone ^† Tandospirone
GABA_AR PAMs	Benzodiazepines: Adinazolam Alprazolam Bromazepam Camazepam Chlordiazepoxide Clobazam Clonazepam Clorazepate Clotiazepam Cloxazolam Diazepam ^# Ethyl loflazepate Etizolam Fludiazepam Halazepam Ketazolam Lorazepam ^# Medazepam Nordazepam Oxazepam Pinazepam Prazepam; Others: Alpidem ^‡ Barbiturates (e.g., phenobarbital) Carisoprodol Carbamates (e.g., meprobamate) Chlormezanone ^‡ Ethanol (alcohol) Etifoxine Imepitoin; Herbs: Kava Skullcap Valerian
Gabapentinoids (α₂δVDCC blockers)	Gabapentin Gabapentin enacarbil Phenibut Pregabalin
Antidepressants	SSRIs (e.g., escitalopram) SNRIs (e.g., duloxetine) SARIs (e.g., trazodone) TCAs (e.g., clomipramine ^#) TeCAs (e.g., mirtazapine) MAOIs (e.g., phenelzine); Others: Agomelatine Bupropion Tianeptine Vilazodone Vortioxetine
Sympatholytics (Antiadrenergics)	Alpha-1 blockers (e.g., prazosin) Alpha-2 agonists (e.g., clonidine, dexmedetomidine, guanfacine) Beta blockers (e.g., propranolol)
Others	Benzoctamine Cannabidiol Cycloserine Fabomotizole Hydroxyzine Kanna Lavender Lorpiprazole Mebicar Mepiprazole Nicotine Opipramol Oxaflozane ^‡ Phenaglycodol Phenibut Picamilon Selank Tiagabine Tofisopam Validolum
^# WHO-EM ^‡ Withdrawn from market Clinical trials: ^† Phase III ^§Never to phase III

Clinical data

Routes of administration	Oral
ATC code	none
Legal status
Legal status	In general: uncontrolled
Identifiers
IUPAC name (3aS,4R,9aR)-6-chloro-2-methyl-4-phenyl-2,3,3a,4,9,9a-hexahydro-1H-benzo[f]isoindole
CAS Number	69175-77-5
PubChem CID	3045392
ChemSpider	2308134
UNII	IX8TM6153H
CompTox Dashboard (EPA)	DTXSID50219221
Chemical and physical data
Formula	C₁₉H₂₀ClN
Molar mass	297.83 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES Clc1ccc3c(c1)[C@@H](c2ccccc2)[C@H]4[C@@H](C3)CN(C4)C

Losindole

See also

References