Pyrrolobenzodiazepines, (PBD) are a class of compound that may have antibiotic or anti-tumor properties. [1]
Some dimeric pyrrolobenzodiazepines are used as the cytotoxic drug payloads in antibody-drug conjugates, for example in loncastuximab tesirine.
Anthramycin, the first PBD monomer, was first synthesized in the 1960s. [2]
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