Lopirazepam

Lopirazepam

Clinical data
Pregnancy category	D
Routes of administration	Oral
ATC code	none
Legal status
Legal status	US: Schedule IV
Identifiers
IUPAC name (RS)-7-Chloro-5-(2-chlorophenyl)-3-hydroxy-1,3-dihydro-2H-pyrido[3,2-e][1,4]diazepin-2-one
CAS Number	42863-81-0
PubChem CID	68672
ChemSpider	61926
UNII	8PDI6DY6GV
CompTox Dashboard (EPA)	DTXSID20866105
ECHA InfoCard	100.050.868
Chemical and physical data
Formula	C14H9Cl2N3O2
Molar mass	322.15 g·mol−1
3D model (JSmol)	Interactive image
Chirality	Racemic mixture
SMILES ClC1=CC=CC=C1C2=NC(C(NC3=C2N=C(Cl)C=C3)=O)O

Lopirazepam (INN) ^[1] is a short-acting benzodiazepine analog of the pyridodiazepine type (specifically, the pyridodiazepine analog of lorazepam) with anxiolytic and hypnotic properties. ^{[2] [3]} It has never been marketed. ^[4]

See also

• Benzodiazepine

References

1. US 4008223,von Bebenburg W, Offermanns H,"6-Aza-3H-1,4-benzodiazepines",issued 15 February 1977, assigned to Deutsche Gold und Silber Scheideanstaltand Evonik Operations GmbH. 
2. Saletu M, Saletu B, Grünberger J, Mader R, Karobath M (1983). "Clinical symptomatology and computer analyzed EEG before, during and after anxiolytic therapy of alcohol withdrawal patients". Neuropsychobiology. 9 (2–3): 119–134. doi:10.1159/000117949. PMID   6353268.
3. Fabian A, Röhmel R, Kubicki S (September 1984). "[Changes in the length of sleep cycles during administration of flurazepam and lopirazepam]". EEG-EMG Zeitschrift für Elektroenzephalographie, Elektromyographie und Verwandte Gebiete (in German). 15 (3): 151–158. PMID   6435999.
4. Triggle DJ, Ganellin CR, MacDonald F (1996). Dictionary of Pharmacological Agents. Vol. 2. Boca Raton: Chapman & Hall/CRC. p. 1232. ISBN   0-412-46630-9. Retrieved on December 31, 2008 through Google Book Search.