Ripazepam

Ripazepam

Identifiers
IUPAC name 1-ethyl-3-methyl-8-phenyl-4,6-dihydropyrazolo[4,3-e][1,4]diazepin-5-one
CAS Number	26308-28-1  Y
PubChem CID	33474
ChemSpider	30896  N
UNII	92000WH9C9
KEGG	C19518  Y
ChEBI	CHEBI:82529
ChEMBL	ChEMBL159298  N
CompTox Dashboard (EPA)	DTXSID1021245
Chemical and physical data
Formula	C15H16N4O
Molar mass	268.320 g·mol−1
3D model (JSmol)	Interactive image
SMILES CCN1C2=C(C(=N1)C)NC(=O)CN=C2C3=CC=CC=C3
InChI InChI=1S/C15H16N4O/c1-3-19-15-13(10(2)18-19)17-12(20)9-16-14(15)11-7-5-4-6-8-11/h4-8H,3,9H2,1-2H3,(H,17,20) N Key:YFHYNLHGFKXAIQ-UHFFFAOYSA-N N
NY  (what is this?)    (verify)

Ripazepam is a pyrazolodiazepinone derivative structurally related to certain benzodiazepine drugs, especially zolazepam. It has anxiolytic effects. ^{[1] [2]}

See also

• Benzodiazepine

References

1. Fitzgerald JE, de la Iglesia FA, McGuire EJ (April 1984). "Carcinogenicity studies in rodents and ripazepam, a minor tranquilizing agent". Fundamental and Applied Toxicology. 4 (2 Pt 1): 178–90. doi:10.1016/0272-0590(84)90118-0. hdl: 2027.42/24852 . PMID   6724192.
2. Baraldi PG, Manfredini S, Periotto V, Simoni D, Guarneri M, Borea PA (May 1985). "Synthesis and interaction of 5-(substituted-phenyl)-3-methyl-6,7-dihydropyrazolo[4,3-e] [1,4]diazepin-8(7H)-ones with benzodiazepine receptors in rat cerebral cortex". Journal of Medicinal Chemistry. 28 (5): 683–5. doi:10.1021/jm50001a025. PMID   2985787.