Crotylbarbital

Last updated
Crotylbarbital
Crotylbarbital.svg
Clinical data
ATC code
  • none
Identifiers
  • 5-but-2-enyl-5-ethyl-1,3-diazinane-2,4,6-trione
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
ECHA InfoCard 100.016.162 OOjs UI icon edit-ltr-progressive.svg
Chemical and physical data
Formula C10H14N2O3
Molar mass 210.233 g·mol−1
3D model (JSmol)
  • O=C1NC(=O)NC(=O)C1(CC)C/C=C/C
  • InChI=1S/C10H14N2O3/c1-3-5-6-10(4-2)7(13)11-9(15)12-8(10)14/h3,5H,4,6H2,1-2H3,(H2,11,12,13,14,15)/b5-3+ Yes check.svgY
  • Key:KNMOHCLEINXVBG-HWKANZROSA-N Yes check.svgY
   (verify)

Crotylbarbital (Mepertan, Kalipnon, Barotal), also known as crotarbital, is a barbiturate derivative developed by Eli Lilly in the 1930s. [1] It has sedative and hypnotic effects, [2] and was used for the treatment of insomnia until it was replaced by newer alternative drugs with fewer side effects and lower risk of overdose.

See also

References

  1. US 2250422,Shonle HA, Doran WJ,"Alkyl-crotyl barbituric acids and their salts",issued 22 July 1941, assigned to Eli Lilly
  2. Walther T, Meyer FP, Puchta K, Walther H (June 1983). "Effect of an acute dose of crotylbarbital on reaction time and attention testing in healthy human subjects". International Journal of Clinical Pharmacology, Therapy, and Toxicology. 21 (6): 306–10. PMID   6136469.