Thialbarbital

Thialbarbital

Clinical data
Other names	Kemithal, 5-(1-cyclohex-2-enyl)-5-prop-2-enyl-2-sulfanylidene-1,3-diazinane-4,6-dione
ATC code	none
Legal status
Legal status	CA: Schedule IV
Identifiers
IUPAC name 5-allyl-5-cyclohex-2-en-1-yl-2-thioxodihydropyrimidine-4,6(1H,5H)-dione
CAS Number	467-36-7  Y as salt:  3546-29-0  Y
PubChem CID	3032306
ChemSpider	2297316  Y
UNII	ENV72C33QD as salt:  RHK739S84F  Y
ChEMBL	ChEMBL2104657  N
CompTox Dashboard (EPA)	DTXSID90861960
ECHA InfoCard	100.006.720
Chemical and physical data
Formula	C13H16N2O2S
Molar mass	264.34 g·mol−1
3D model (JSmol)	Interactive image
SMILES O=C1NC(=S)NC(=O)C1(C2/C=C\CCC2)C\C=C
InChI InChI=1S/C13H16N2O2S/c1-2-8-13(9-6-4-3-5-7-9)10(16)14-12(18)15-11(13)17/h2,4,6,9H,1,3,5,7-8H2,(H2,14,15,16,17,18) Y Key:PXLVRFQEBVNJOH-UHFFFAOYSA-N Y
NY  (what is this?)    (verify)

Thialbarbital (Intranarcon) is a barbiturate derivative invented in the 1960s. It has sedative effects, and was used primarily for induction in surgical anaesthesia. ^[1] Thialbarbital is short acting and has less of a tendency to induce respiratory depression than other barbiturate derivatives such as pentobarbital. ^[2]

See also

• Thiamylal

References

1. Golovchinsky VB, Plehotkina SI (July 1971). "Difference in the sensitivity of the cerebral cortex and midbrain reticular formation to the action of diethylether and thialbarbital". Brain Research. 30 (1): 37–47. doi:10.1016/0006-8993(71)90004-7. PMID   5092630.
2. Bercovitz AB, Godke RA, Biellier HV, Short CE (March 1975). "Surgical anesthesia in turkeys with thialbarbital sodium". American Journal of Veterinary Research. 36 (3): 301–2. PMID   1115429.